ReviewJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018
Intra- and interatrial conduction abnormalities: hemodynamic and arrhythmic significance.
Review in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07305194 (Study of Atrial High-Rate Episode Burden in Patients Undergoing Concurrent Bachmann Bundle Area Pacing and Left Bundle Branch Pacing , Compared With Either Left Bundle Branch Pacing or Conventional Right Ventricular Pacing.), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Atrial High-Rate Episode Burden in Patients Undergoing Concurrent Bachmann Bundle Area Pacing and Left Bundle Branch Pacing , Compared With Either Left Bundle Branch Pacing or Conventional Right Ventricular Pacing.
Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Direct comparison of transvenous and leadless Bachmann bundle area pacing in the same patient.HeartRhythm case reports · 2026Article
- Comparison of Invasive Left Atrial Pressure Between Bachmann's Bundle and Right Atrial Appendage Pacing.Pacing and clinical electrophysiology : PACE · 2026Review
- Correction of advanced interatrial block with Bachmann's bundle pacing.HeartRhythm case reports · 2025Article
- Leadless Atrial Pacing Targeting Bachmann's Bundle for Atrial Resynchronization.JACC. Case reports · 2025Article
- The Influence of Interatrial Conduction Disorders on Atrial Mechanical Function - Atrial Strain and Pulmonary Veins Reversal Flow in Patients with COVID-19.Reviews in cardiovascular medicine · 2025Article
- Advanced Interatrial Block across the Spectrum of Renal Function.Medicina (Kaunas, Lithuania) · 2024Article
- Exercise-Induced Electrocardiographic Changes in Healthy Young Males with Early Repolarization Pattern.Diagnostics (Basel, Switzerland) · 2024Article
- Atrial Pacing Negatively Affects Left Atrial Morphological and Functional Parameters Similarly to Atrioventricular Dyssynchrony.Medicina (Kaunas, Lithuania) · 2024Article
- P-wave durations from automated electrocardiogram analysis to predict atrial fibrillation and mortality in heart failure.ESC heart failure · 2023Article
- P-wave parameters and their association with thrombi and spontaneous echo contrast in the left atrial appendage.Clinical cardiology · 2023Article
- Electro-Mechanical Alterations in Atrial Fibrillation: Structural, Electrical, and Functional Correlates.Journal of cardiovascular development and disease · 2023Review
- Electrocardiographic Changes Associated with Early Repolarization Pattern in Healthy Young Males.Medicina (Kaunas, Lithuania) · 2022Article
- Safety, Efficacy and Prognostic Benefit of Atrial Fibrillation Ablation in Heart Failure with Preserved Ejection Fraction.Arrhythmia & electrophysiology review · 2022Review
- Left atrial reentrant tachycardia with interatrial dissociation mimicking accelerated idioventricular rhythm in a patient with a cardiac resynchronization defibrillator.HeartRhythm case reports · 2021Article
- Interatrial conduction block-related atrioventricular dyssynchrony treated with dual-site atrial pacing.HeartRhythm case reports · 2021Article
- Individualised Approaches for Catheter Ablation of AF: Patient Selection and Procedural Endpoints.Arrhythmia & electrophysiology review · 2019Review
- Interatrial block and ischemic stroke.Journal of thoracic disease · 2018Article
- Intra-Atrial Block: Definition and Relationship to Atrial Fibrillation and Other Adverse Outcomes.Journal of atrial fibrillationReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Alterations of normal intra- and interatrial conduction are a common outcome of multiple cardiovascular conditions. They arise most commonly in the context of advanced age, cardiovascular risk factors, organic heart disease, atrial fibrosis, and left atrial enlargement. Interatrial block (IAB), the most frequent and extensively studied atrial conduction disorder, affects up to 20% of the general primary care population. IAB can be partial (P wave duration ≥ 120 ms on any of the 12 ECG leads) or advanced (P wave ≥ 120 ms and biphasic morphology (positive-negative) in inferior leads). Advanced IAB is an independent risk factor for supraventricular tachyarrhythmias and embolic stroke in a variety of clinical settings. Advanced IAB is a cause of left atrial electromechanical dysfunction and left atrioventricular dyssynchrony and has been associated with left ventricular diastolic dysfunction. P wave duration is associated with cardiovascular and all-cause mortality in the general population. Atrial conduction abnormalities should be identified as markers of atrial remodeling, prognostic indicators, and, in the case of advanced IAB, a true arrhythmologic syndrome. IAB and other P wave abnormalities should prompt the search for associated conditions, the treatment of which may partially reverse atrial remodeling or prevent it if administered upstream. Future studies will help define the role of preventive therapeutic interventions in high-risk patients, including antiarrhythmic drug therapy and oral anticoagulation. Implications for the treatment of heart failure and for pacing should also be further investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.