SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2018
What are the risk factors for surgical site infection after spinal fusion? A meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between malnutrition and surgical site wound infection among spinal surgery patients: A meta-analysis.International wound journal · 2023Pooled it
- Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.North American Spine Society journal · 2026Article
- Comparison of postoperative infection risk with and without topical vancomycin in adult posterior spinal fusion: a propensity-matched cohort study of 126,910 patients.Spine deformity · 2026Article
- Does the combination of pulsed lavage and negative pressure dressings reduce infection rates after posterior spinal arthrodesis in pediatric scoliosis ?Spine deformity · 2026Article
- Risk stratification of surgical site infection in high-risk spine surgery under prophylactic ciNPWT.BMC musculoskeletal disorders · 2026Observational
- Associated factors for surgical site infection with spinal instrumentation surgery.Scientific reports · 2025Article
- Risk factors and predictive model for early surgical site infection following single-level PLIF in diabetic patients.Frontiers in surgery · 2025Article
- Association between postoperative intravenous methylprednisolone and surgical site infection in posterior lumbar fusion surgery: a retrospective single-center study.BMC musculoskeletal disorders · 2024Article
- Prophylactic closed-incisional negative pressure wound therapy following posterior instrumented spinal fusion: a single surgeon's experience and cost-benefit analysis.Neurosurgical review · 2024Article
- Reduction of Instrumentation-Related Spine Surgical Site Infections After Optimization of Surgical Techniques. A Single Center Retrospective Analysis.Global spine journal · 2024Article
- Investigating the efficacy of vacuum sealing drainage versus traditional negative pressure drainage in treating deep incision infections following posterior cervical internal fixation-a retrospective cohort study.European journal of medical research · 2024Article
- Surgical and procedural antibiotic prophylaxis in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.Trauma surgery & acute care open · 2024Article
- Risk factors for incisional complications after lumbar internal fixation via posterior midline approach: A case-control study of 455 consecutive cases.International wound journal · 2023Article
- Local contamination is a major cause of early deep wound infections following open posterior lumbosacral fusions.Spine deformity · 2023Article
- Association between immediate postoperative hypoalbuminemia and surgical site infection after posterior lumbar fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Does Tobacco Smoking Affect the Postoperative Outcome of MIS Lumbar Decompression Surgery?Journal of clinical medicine · 2023Article
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- The risk factors of the postoperative poor wound healing in spinal tuberculosis patients: A single centre retrospective cohort study.International wound journal · 2022Article
- Safety and efficacy of negative pressure wound therapy in treating deep surgical site infection after lumbar surgery.International orthopaedics · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAlthough many risk factors for surgical site infection (SSI) following spinal fusion have been described in the literature, methodologies and study cohorts vary widely. Patient- and procedure-specific risk factors for (SSI) can be identified via a meta-analysis. We sought to review the existing data and isolate significant risk factors for SSI in patients undergoing thoracolumbar spinal fusion.
methodsThe literature was searched through December of 2016. Studies including adult patients undergoing thoracolumbar spinal fusion surgery (single or multilevel, anterior, posterior or combined approach) were identified. Only studies that included an odds ratio (OR) for SSI or sufficient data to calculate it were included. A meta-analysis was performed using RevMan 5.1. Depending on heterogeneity (I
results6482 manuscripts were identified and reviewed. 29 manuscripts with 374,488 patients met the criteria for inclusion. Twelve risk factors were assessed by the meta-analysis and grouped into two categories (patient related and procedure related). Significant patient-related factors for SSI included obesity, diabetes, ASA score, tobacco use and revision status. Procedure-related risk factors included operative time, use of osteotomy, fusion length and extension of fusion to the sacrum or pelvis.
conclusionsThis meta-analysis identified significant risk factors for SSI following spine arthrodesis. These included potentially modifiable factors such as obesity, diabetes, smoking status and procedure-related parameters. Non-modifiable risk factors were identified, including ASA score and age. These factors may prove useful for patient counseling as well as surgical planning. LEVEL OF EVIDENCE: Level III (Meta-analysis including studies with a level of evidence of III or higher). These slides can be retrieved under Electronic Supplementary Material.
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