Evidence map›Paper›PMID 30128730›Full record

ArticleRheumatology international2019

Raynaud's phenomenon in Northern Sweden: a population-based nested case-control study.

Albin Stjernbrandt, Hans Pettersson, Ingrid Liljelind, Tohr Nilsson, Jens Wahlström

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
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  4. Raynaud's phenomenon in the feet of Arctic open-pit miners.International journal of circumpolar health · 2024
    Article
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  12. Adverse health manifestations in the hands of vibration exposed carpenters - a cross sectional study.Journal of occupational medicine and toxicology (London, England) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Albin StjernbrandtOccupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden. albin.stjernbrandt@umu.se.ORCID 0000-0001-6082-8465
Hans PetterssonOccupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden.ORCID 0000-0001-7077-2389
Ingrid LiljelindOccupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden.ORCID 0000-0002-5936-1172
Tohr NilssonOccupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden.ORCID 0000-0003-2789-6321
Jens WahlströmOccupational and Environmental Medicine, Umeå University, 901 87, Umeå, Sweden.ORCID 0000-0002-2359-509X
Umeå University · SE

Funding

Västerbotten Läns Landsting VLL-646641
6 · The paper itself

Abstract

The aim of this study was to determine the association between individual and external exposure factors, and the reporting of Raynaud's phenomenon, with or without concomitant cold sensitivity. In a population-based nested case-control study, cases with Raynaud's phenomenon (N = 578), and matched controls (N = 1156), were asked to respond to a questionnaire focusing on different risk factors. Univariate and multiple conditional logistic regression were performed. Analyses were stratified according to whether the cases reported cold sensitivity or not. In total, 1400 out of 1734 study subjects answered the questionnaire (response rate 80.7%). In the final multiple model, the factor with the strongest association to Raynaud's phenomenon, with and without cold sensitivity, was previous frostbite affecting the hands (OR 12.44; 95% CI 5.84-26.52 and OR 4.01; 95% CI 1.78-9.01, respectively). Upper extremity nerve injury was associated to reporting Raynaud's phenomenon and cold sensitivity (OR 2.23; 95% CI 1.29-3.85), but not Raynaud's phenomenon alone. Reporting any exposure to hand-arm vibration or cumulative cold exposure was significant in univariate analyses for cases with both Raynaud's phenomenon and cold sensitivity, but not in the multiple model. Raynaud's phenomenon is strongly associated to previous cold injury, with a larger effect size among those who also report cold sensitivity. The fact that only upper extremity nerve injury differed significantly between case groups in our multiple model offers additional support to the neural basis for cold sensitivity.

Indexed as

AdultAgedCase-Control StudiesCold TemperatureFemaleHumansLogistic ModelsMaleMiddle AgedRaynaud DiseaseRisk FactorsCold exposureEpidemiologyFrostbiteHandOccupational exposureRisk factors

Identifiers

PMID30128730
OpenAlexW2888611217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.