Evidence map›Paper›PMID 30128720›Full record

Trial reportGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2019

A feasibility study of laparoscopic total gastrectomy for clinical stage I gastric cancer: a prospective multi-center phase II clinical trial, KLASS 03.

Woo Jin Hyung, Han-Kwang Yang, Sang-Uk Han, Young-Jun Lee, Joong-Min Park, Jin Jo Kim, Oh Kyung Kwon, Seong Ho Kong, Hyoung-Il Kim, Hyuk-Joon Lee and 12 more

2 registry-linked trialsOpen access · bronzeAbstract readClinical Trial, Phase IIMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 113 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 6 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04710758 narecruitingnot on this mapstarted 2021, after this paper: background citation

Prospective Randomized Controlled Multicenter Clinical Trial For Comparison Of Long-term Outcomes Between Laparoscopic And Open Total Gastrectomy In Patients With Locally Advanced Gastric Cancer

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2021 to 2028Enrolled1,018ConditionsStomach NeoplasmsArmsLaparoscopic total gastrectomy, Open total gastrectomy
NCT06263205 nacompletednot on this mapstarted 2024, after this paper: background citation

A Randomized, Open-Label, Multicenter, Non-Inferiority Clinical Trial Comparing No Wound Dressing Change Versus Routine Wound Dressing Change After Gastrointestinal Surgery

TypeinterventionalSponsorFudan UniversityRan2024 to 2025Enrolled1,138ConditionsGastrointestinal Tumors, Surgical Wound Infection, Pain, PostoperativeArmsNon-Dressing of Surgical Wound, Regular Dressing Change of Surgical Wound
3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 6 syntheses or guidelines pooled it, 174 citations in OpenAlex.

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  3. Evolution of treatment in gastric cancer- a systematic review.Journal of the Egyptian National Cancer Institute · 2022
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  4. [Evidence in minimally invasive oncological gastric surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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  12. Open versus minimally invasive total gastrectomy after neoadjuvant chemotherapy: results of a European randomized trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 1 country.

Woo Jin HyungDepartment of Surgery, Yonsei University College of Medicine, Seoul, South Korea.
Han-Kwang YangDepartment of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Sang-Uk HanDepartment of Surgery, Ajou University School of Medicine, Suwon, South Korea.
Young-Jun LeeDepartment of Surgery, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, South Korea.
Joong-Min ParkDepartment of Surgery, Chung-Ang University College of Medicine, Seoul, South Korea.
Jin Jo KimDepartment of Surgery, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Incheon, South Korea.
Oh Kyung KwonDepartment of Surgery, Kyungpook National University Medical Center, Daegu, South Korea.
Seong Ho KongDepartment of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Hyoung-Il KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, South Korea.
Hyuk-Joon LeeDepartment of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Wook KimDepartment of Surgery, Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea.
Seung Wan RyuDepartment of Surgery, Keimyung University School of Medicine, Daegu, South Korea.
Sung-Ho JinDepartment of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea.
Sung Jin OhDepartment of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Keun Won RyuCenter for Gastric Cancer, Research Institute and Hospital, National Cancer Center, Goyang, South Korea.
Min-Chan KimDepartment of Surgery, Dong-A University College of Medicine, Busan, South Korea.
Hye-Seong AhnDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, South Korea.
Young Kyu ParkDepartment of Surgery, Chonnam National University Hwasoon Hospital, Hwasun, South Korea.
Young-Ho KimDepartment of Surgery, Kyung Hee University School of Medicine, Seoul, South Korea.
Sun-Hwi HwangDepartment of Surgery, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Jong Won KimDepartment of Surgery, Chung-Ang University College of Medicine, Seoul, South Korea.
Gyu Seok ChoDepartment of Surgery, Soonchunhyang University College of Medicine, 170-Jomaru-ro, Bucheon-si, Gyeonggi-do, South Korea. gschogs@schmc.ac.kr.
Seoul National University · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KRYonsei University · KRAjou University · KRChonnam National University Hwasun Hospital · KRChung-Ang University · KRDong-A University · KRGyeongsang National University · KRInje University Haeundae Paik Hospital · KRKeimyung University · KRKorea Institute of Radiological and Medical Sciences · KRKyung Hee University · KRKyungpook National University Medical Center · KRNational Cancer Center · KRPusan National University Yangsan Hospital · KRSoonchunhyang University · KRThe Catholic University of Korea Yeouido St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith improved short-term surgical outcomes, laparoscopic distal gastrectomy has rapidly gained popularity. However, the safety and feasibility of laparoscopic total gastrectomy (LTG) has not yet been proven due to the difficulty of the technique. This single-arm prospective multi-center study was conducted to evaluate the use of LTG for clinical stage I gastric cancer.

methodsBetween October 2012 and January 2014, 170 patients with pathologically proven, clinical stage I gastric adenocarcinoma located at the proximal stomach were enrolled. Twenty-two experienced surgeons from 19 institutions participated in this clinical trial. The primary end point was the incidence of postoperative morbidity and mortality at postoperative 30 days. The severity of postoperative complications was categorized according to Clavien-Dindo classification, and the incidence of postoperative morbidity and mortality was compared with that in a historical control.

resultsOf the enrolled patients, 160 met criteria for inclusion in the full analysis set. Postoperative morbidity and mortality rates reached 20.6% (33/160) and 0.6% (1/160), respectively. Fifteen patients (9.4%) had grade III or higher complications, and three reoperations (1.9%) were performed. The incidence of morbidity after LTG in this trial did not significantly differ from that reported in a previous study for open total gastrectomy (18%).

conclusionsLTG performed by experienced surgeons showed acceptable postoperative morbidity and mortality for patients with clinical stage I gastric cancer.

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overFeasibility StudiesFemaleGastrectomyHumansIncidenceLaparoscopyMaleMiddle AgedPostoperative ComplicationsProspective StudiesStomach NeoplasmsTreatment OutcomeGastric cancerLaparoscopyTotal gastrectomy

Identifiers

PMID30128720
OpenAlexW2888148025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.