Evidence map›Paper›PMID 30128626›Full record

ArticleMolecular biology reports2018

Uncoupling Warburg effect and stemness in CD133

Pavani Koka, Reddy Sailaja Mundre, Rohini Rangarajan, Yamini Chandramohan, Raghunandha Kumar Subramanian, Anuradha Dhanasekaran

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pavani KokaCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.ORCID http://orcid.org/0000-0002-0549-5896
Reddy Sailaja MundreCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.ORCID http://orcid.org/0000-0003-0983-1647
Rohini RangarajanCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.ORCID http://orcid.org/0000-0003-0216-9291
Yamini ChandramohanCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.ORCID http://orcid.org/0000-0001-9814-9580
Raghunandha Kumar SubramanianCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India.ORCID http://orcid.org/0000-0003-3165-0703
Anuradha DhanasekaranCentre for Biotechnology, Anna University, Chennai, Tamil Nadu, 600025, India. anu@annauniv.edu.ORCID http://orcid.org/0000-0002-0195-9681
Anna University, Chennai · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) which are known to be residing deep inside the core of the tumor in its hypoxia niche is responsible for relapse of cancers. Owing to this hypoxic niche, the residing CSCs simultaneously fuel their stemness, cancerous and drug resistance properties. Attributes of CSCs are still not properly understood in its hypoxia niche. Addressing this, we sorted CSCs from Saos-2 (osteosarcoma) cell line using CD133 antibody. The CD133

Indexed as

AC133 AntigenBone NeoplasmsCell Line, TumorCell MovementCell ProliferationDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticGlycolysisHumansHypoxiaNeoplasm Recurrence, LocalNeoplastic Stem CellsOsteosarcomaOxidative PhosphorylationSignal TransductionAC133 AntigenCancer stem cellsHypoxiaWarburg effect

Identifiers

PMID30128626
OpenAlexW2888482325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.