Evidence map›Paper›PMID 30128617›Full record

ArticleEuropean radiology2019

Diastolic dysfunction evaluated by cardiac magnetic resonance: the value of the combined assessment of atrial and ventricular function.

Giovanni Donato Aquaro, Fausto Pizzino, Anna Terrizzi, Scipione Carerj, Bijoy K Khandheria, Gianluca Di Bella

Abstract read
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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Observational
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  3. [Using CT to Evaluate Cardiac Function].Journal of the Korean Society of Radiology · 2024
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  4. Reference data for left ventricular filling and atrial function in children using cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Giovanni Donato AquaroFondazione G. Monasterio CNR-Toscana, Via Giuseppe Moruzzi, 1, 56124, Pisa, Italy. aquaro@ftgm.it.
Fausto PizzinoScuola Superiore Sant'Anna di Studi Universitari e di Perfezionamento, Pisa, Italy.
Anna TerrizziDipartimento di Medicina Clinica e Sperimentale, University of Messina, Messina, Italy.
Scipione CarerjDipartimento di Medicina Clinica e Sperimentale, University of Messina, Messina, Italy.
Bijoy K KhandheriaAurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, Milwaukee, WI, USA.
Gianluca Di BellaDipartimento di Medicina Clinica e Sperimentale, University of Messina, Messina, Italy.
University of Messina · ITAurora St. Luke's Medical Center · USFondazione Toscana Gabriele Monasterio · ITScuola Superiore Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe sought to evaluate the role of cardiac magnetic resonance imaging (CMR) in the evaluation of diastolic function by a combined assessment of left ventricular (LV) and left atrial (LA) function in a cohort of subjects with various degrees of diastolic dysfunction (DD) detected by echocardiography.

methodsForty patients with different stages of DD and 18 healthy controls underwent CMR. Short-axis cine steady-state free precession images covering the entire LA and LV were acquired. Parameters of diastolic function were measured by the analysis of the LV and LA volume/time (V/t) curves and the respective derivative dV/dt curves.

resultsAt receiver operating characteristic (ROC) curve analysis, the peak of emptying rate A indexed by the LV filling volume with a cut-off of 3.8 was able to detect patients with grade I DD from other groups (area under the curve [AUC] 0.975, 95% confidence interval [CI] 0.86-1). ROC analysis showed that LA ejection fraction with a cut-off of ≤36% was able to distinguish controls and grade I DD patients from those with grade II and grade III DD (AUC 0.996, 95% CI 0.92-1, p < 0.001). The isovolumetric pulmonary vein transit ratio with a cut-off of 2.4 allowed class III DD to be distinguished from other groups (AUC 1.0, 95%CI 0.93-1, p < 0.001).

conclusionsAnalysis of LV and LA V/t curves by CMR may be useful for the evaluation of DD. KEY POINTS: • Combined atrial and ventricular volume/time curves allow evaluation of diastolic function. • Atrial emptying fraction allows distinction between impaired relaxation and restrictive/pseudo-normal filling. • Isovolumetric pulmonary vein transit ratio allows distinction between restrictive and pseudo-normal filling.

Indexed as

Atrial Function, LeftDiastoleMagnetic Resonance ImagingAdultAgedArea Under CurveCardiomyopathy, HypertrophicEchocardiographyFemaleHeart AtriaHeart FailureHumansMaleMiddle AgedPulmonary VeinsROC CurveDiastoleHeart failureHypertrophic cardiomyopathyMagnetic resonancePhysiology: atrial function

Identifiers

PMID30128617
OpenAlexW2888320918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.