Evidence map›Paper›PMID 30128604›Full record

ReviewCurrent neurology and neuroscience reports2018

Impact of Recent Studies for the Treatment of Intracerebral Hemorrhage.

Jochen A Sembill, Hagen B Huttner, Joji B Kuramatsu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. [Acute treatment of intracerebral hemorrhage].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jochen A SembillDepartment of Neurology, University Hospital Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany.
Hagen B HuttnerDepartment of Neurology, University Hospital Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany.
Joji B KuramatsuDepartment of Neurology, University Hospital Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany. joji.kuramatsu@uk-erlangen.de.
Universitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe present review will cover most recent and important studies on acute treatment of intracerebral hemorrhage (ICH). RECENT

findingsOverly pessimistic prognostication in ICH may deny meaningful recovery achieved by specialized neurocritical care. Hematoma enlargement represents the most important target of acute ICH care, which is reduced by aggressive blood pressure management (targeting a systolic blood pressure of 140 mmHg) and appropriate hemostatic treatment especially in anticoagulation-associated ICH (INR reversal using prothrombin complex concentrates, eventually idarucizumab, andexanet, or tranexamic acid). Surgical treatment strategies involving fibrinolytics either used for direct hematoma lysis or used for intraventricular clot removal with/without additional lumbar drainage show great promise. Further novel treatment strategies are underway and need validation or evaluation strongly warranting well-designed future ICH research. Several randomized and large-sized observational studies have considerably expanded the field and the evidence on how to treat acute ICH patients. Yet, the one breakthrough intervention to improve functional outcome is still missing, though various treatment concepts possibly interacting with one another have been evaluated and such treatment bundle may improve patients' outcome.

Indexed as

AnticoagulantsBlood Coagulation FactorsBlood PressureCerebral HemorrhageCritical CareFactor XaHematomaHumansObservational Studies as TopicRandomized Controlled Trials as TopicRecombinant ProteinsAnticoagulantsBlood Coagulation FactorsFactor Xaprothrombin complex concentratesPRT064445Recombinant ProteinsHemorrhagic strokeIntracerebral hemorrhageNeurocritical care

Identifiers

PMID30128604
OpenAlexW2888003226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.