ArticleNeuroImage. Clinical2018
The significance of brain oscillations in motor sequence learning: Insights from Parkinson's disease.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of MEG-based studies in Parkinson's disease: The motor system and beyond.Human brain mapping · 2019Pooled it
- Suppression of Motor Sequence Learning and Execution Through Anodal Cerebellar Transcranial Electrical Stimulation.Cerebellum (London, England) · 2023Trial
- Perceptual Temporal Structure Supports Rhythm Learning and Enhances Theta Oscillations When Perception and Action Are Dissociated.Brain sciences · 2026Article
- Absence of evidence for post-training tDCS effects on motor memory consolidation and premotor-primary motor cortex interaction: a resting-state EEG study.Frontiers in human neuroscience · 2026Article
- Cortical beta power modulation is asymmetric and reduced during movement execution and inhibition in Parkinson's disease.Neurobiology of disease · 2025Article
- Atypical Beta Oscillatory Dynamics Are Related to Poor Procedural Learning in Children With Developmental Coordination Disorder.Developmental science · 2025Article
- The Supplementary Motor Area as a Flexible Hub Mediating Behavioral and Neuroplastic Changes in Motor Sequence Learning: A TMS and TMS-EEG Study.Neuroscience bulletin · 2025Article
- GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Exploring the Impact of Declarative Learning on the Consolidation of Acquired Motor Skills Under Valence Feedback.Human brain mapping · 2025Article
- Dysfunction of motor cortices in Parkinson's disease.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
- Top-down and bottom-up oscillatory dynamics regulate implicit visuomotor sequence learning.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Training-related changes in neural beta oscillations associated with implicit and explicit motor sequence learning.Scientific reports · 2024Article
- Research progress on the intervention of cognitive function using transcranial alternating current stimulation technology.Frontiers in psychology · 2024Article
- Theta Signal Transfer from Parietal to Prefrontal Cortex Ignites Conscious Awareness of Implicit Knowledge during Sequence Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Aberrant neural processing of event boundaries in persons with Parkinson's disease.Scientific reports · 2023Article
- Continuous and intermittent theta burst stimulation of primary visual cortex do not modulate resting state functional connectivity: A sham-controlled multi-echo fMRI study.Brain and behavior · 2023Article
- Neural basis of implicit motor sequence learning: Modulation of cortical power.Psychophysiology · 2023Article
- Cortical effects of wrist tendon vibration during an arm tracking task in chronic stroke survivors: An EEG study.PloS one · 2023Article
- A Single Bout of High-Intensity Cardiovascular Exercise Does Not Enhance Motor Performance and Learning of a Visuomotor Force Modulation Task, but Triggers Ipsilateral Task-Related EEG Activity.International journal of environmental research and public health · 2021Article
- Movement-related EEG signatures associated with freezing of gait in Parkinson's disease: an integrative analysis.Brain communications · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor sequence learning plays a pivotal role in various everyday activities. Motor-cortical beta oscillations have been suggested to be involved in this type of learning. In Parkinson's disease (PD), oscillatory activity within cortico-basal-ganglia circuits is altered. Pathologically increased beta oscillations have received particular attention as they may be associated with motor symptoms such as akinesia. In the present magnetoencephalography (MEG) study, we investigated PD patients and healthy controls (HC) during implicit motor sequence learning with the aim to shed light on the relation between changes of cortical brain oscillations and motor learning in PD with a particular focus on beta power. To this end, 20 PD patients (ON medication) and 20 age- and sex-matched HC were trained on a serial reaction time task while neuromagnetic activity was recorded using a 306-channel whole-head MEG system. PD patients showed reduced motor sequence acquisition and were more susceptible to interference by random trials after training on the task as compared to HC. Behavioral differences were paralleled by changes at the neurophysiological level. Diminished sequence acquisition was paralleled by less training-related beta power suppression in motor-cortical areas in PD patients as compared to HC. In addition, PD patients exhibited reduced training-related theta activity in motor-cortical areas paralleling susceptibility to interference. The results support the hypothesis that the acquisition of a new motor sequence relies on suppression of motor-cortical beta oscillations, while motor-cortical theta activity might be related to stabilization of the learned sequence as indicated by reduced susceptibility to interference. Both processes appear to be impaired in PD.
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