Evidence map›Paper›PMID 30128271›Full record

ArticleRespiratory medicine case reports2018

A case series describing common radiographic and pathologic patterns of hard metal pneumoconiosis.

J Chiarchiaro, L R Tomsic, S Strock, K L Veraldi, M Nouraie, J Sellares, K O Lindell, L A Ortiz, F C Sciurba, R F Kucera and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

J ChiarchiaroDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
L R TomsicDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
S StrockDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
K L VeraldiDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
M NouraieDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
J SellaresDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
K O LindellDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
L A OrtizDivision of Occupational Medicine, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
F C SciurbaDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
R F KuceraExcela Westmoreland Hospital, Greensburg PA, USA.
S A YousemDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
C R FuhrmanDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
D J KassDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
K F GibsonDivision of Pulmonary Allergy and Critical Care, University of Pittsburgh School of Medicine, Pittsburgh PA, USA.
University of Pittsburgh · USUniversity of Pittsburgh at Greensburg · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHard metal pneumoconiosis is a rare but serious disease of the lungs associated with inhalational exposure to tungsten or cobalt dust. Little is known about the radiologic and pathologic characteristics of this disease and the efficacy of treating with immunosuppression.

objectiveWe describe the largest cohort of patients with hard metal pneumoconiosis in the literature, including radiographic and pathologic patterns as well as treatment options.

methodsWe retrospectively identified patients from the University of Pittsburgh pathology registry between the years of 1985 and 2016. Experts in chest radiology and pulmonary pathology reviewed the cases for radiologic and pathologic patterns.

resultsWe identified 23 patients with a pathologic pattern of hard metal pneumoconiosis. The most common radiographic findings were ground glass opacities (93%) and small nodules (64%). Of 20 surgical biopsies, 17 (85%) showed features of giant cell interstitial pneumonia. Most patients received systemic corticosteroids and/or steroid-sparing immunosuppression.

conclusionsHard metal pneumoconiosis is characterized predominately by radiographic ground glass opacities and giant cell interstitial pneumonia on histopathology. Systemic corticosteroids and steroid-sparing immunosuppression are common treatment options.

Indexed as

Giant cell interstitial pneumoniaHard metal pneumoconiosisInterstitialLung diseases

Identifiers

PMID30128271
PMCPMC6098207
OpenAlexW2887637640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.