ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018
The Dual Functional Reflecting Iris of the Zebrafish.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Lysosome-related organelles orchestrate guanine crystal formation in pigment cells.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The Molecular Basis of Growth Control in Guanine Crystals.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- pH variations enable guanine crystal formation within iridosomes.Nature chemical biology · 2026Article
- Comparative analysis of the structure and crystallin composition of the lenses of freshwater fish and gastropods with respect to their vision.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
- Genetic control over biogenic crystal morphogenesis in zebrafish.Nature chemical biology · 2025Article
- Guanine crystal formation by the unicellular organism Phacotus lenticularis is part of a cellular stress response.PloS one · 2025Article
- The physical and cellular mechanism of structural color change in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Mapping the Metabolic Characteristics and Perturbation of AdultMetabolites · 2024Article
- Structure Determination of Biogenic Crystals Directly from 3D Electron Diffraction Data.Crystal growth & design · 2024Article
- Light and scanning electron microscopy of the eye ofFrontiers in veterinary science · 2024Article
- Guanine crystal formation by bacteria.BMC biology · 2023Article
- Macromolecular sheets direct the morphology and orientation of plate-like biogenic guanine crystals.Nature communications · 2023Article
- Plate-like Guanine Biocrystals Form via Templated Nucleation of Crystal Leaflets on Preassembled Scaffolds.Journal of the American Chemical Society · 2022Article
- Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites.Journal of the American Chemical Society · 2022Article
- Melanins as Sustainable Resources for Advanced Biotechnological Applications.Global challenges (Hoboken, NJ) · 2021Review
- In situ differentiation of iridophore crystallotypes underlies zebrafish stripe patterning.Nature communications · 2020Article
- Fast, easy and early (larval) identification of transparent mutant zebrafish using standard fluorescence microscopy.F1000Research · 2020Article
- The fenestrae-associated protein Plvap regulates the rate of blood-borne protein passage into the hypophysis.Development (Cambridge, England) · 2019Article
- Fate plasticity and reprogramming in genetically distinct populations ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The Dual Functional Reflecting Iris of the Zebrafish.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many marine organisms have evolved a reflective iris to prevent unfocused light from reaching the retina. The fish iris has a dual function, both to camouflage the eye and serving as a light barrier. Yet, the physical mechanism that enables this dual functionality and the benefits of using a reflective iris have remained unclear. Using synchrotron microfocused diffraction, cryo-scanning electron microscopy imaging, and optical analyses on zebrafish at different stages of development, it is shown that the complex optical response of the iris is facilitated by the development of high-order organization of multilayered guanine-based crystal reflectors and pigments. It is further demonstrated how the efficient light reflector is established during development to allow the optical functionality of the eye, already at early developmental stages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.