Imaging findings in the progression of a giant cell glioblastoma.

Ryan Turner, Samuel Matthys, John Heymann, Benjamin Gelman

Open access · goldAbstract readCase Reports

In one paragraph

Article in Radiology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.4field-weighted citation impact, top 34% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma.Neuro-oncology advances
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ryan TurnerThe University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

Samuel MatthysThe University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

John HeymannThe University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

Benjamin GelmanThe University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

The University of Texas Medical Branch at Galveston · US

Funding

Texas NeuroAIDS Research CenterU24MH100930 · NIMH · UNIVERSITY OF TEXAS MED BR GALVESTON · PI GELMAN, BENJAMIN B. · 2013 to 2023

$12.1M

NIMH NIH HHS U24 MH100930

6 · The paper itself

Abstract

First described in 1909, giant cell glioblastoma (GC) is a histologic variant of glioblastoma multiforme (GBM) that accounts for 1% of cases of primary GBM. It is characterized by a predominance of bizarre giant cells with abundant eosinophilic cytoplasm, and may portend an improved prognosis over classic GBM. Due to the rarity of GC, there is a paucity of reports that describe its associated radiologic findings. This case report chronicles the progression of a GC that was incidentally discovered in a 74-year-old male with coincident subdural hematoma and empyema. Serial brain imaging was obtained as part of this patient's continued work-up that documents the radiologic characteristics of the GC over a period of months. To our knowledge, this manuscript is the most extensive radiologic documentation of the progression of GC to date.

Indexed as

Brain imagingBrain tumorGiant cellGlioblastomaMultiforme

Identifiers

PMID30128062

DOI10.1016/j.radcr.2018.07.010

PMCPMC6097408

OpenAlexW2885135285

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.