Evidence map›Paper›PMID 30128034›Full record

ArticleTheranostics2018

Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice.

Virender Kumar, Vaibhav Mundra, Yang Peng, Yingzhe Wang, Chalet Tan, Ram I Mahato

Abstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  14. Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma.Journal of controlled release : official journal of the Controlled Release Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Virender KumarDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Vaibhav MundraDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Yang PengDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Yingzhe WangDepartment of Pharmaceutics and Drug Delivery, University of Mississippi, MS 38677, USA.
Chalet TanDepartment of Pharmaceutics and Drug Delivery, University of Mississippi, MS 38677, USA.
Ram I MahatoDepartment of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Funding

Polymeric Nanomedicines of Hedgehog Inhibitor and miRNA for Treating Pancreatic CancerR01GM113166 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BATRA, SURINDER K., MAHATO, RAM I. · 2015 to 2018
$1.4M
NIGMS NIH HHS R01 GM113166
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MicellesAnilidesAnimalsAnimal StructuresAntineoplastic AgentsCarbocyaninesChromatography, LiquidDisease Models, AnimalDrug CarriersFluorometryMiceMicroRNAsOptical ImagingPancreatic NeoplasmsPlasmaPyridinesAnilidesAntineoplastic AgentsCarbocyaninesCY5.5 cyanine dyeDrug CarriersHhAntag691MicellesMicroRNAsmirnlet7 microRNA, humanPyridinesbiodistributionGDC-0449let-7bmicellespancreatic cancerpharmacokinetics

Identifiers

PMID30128034
PMCPMC6096395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.