Evidence map›Paper›PMID 30127962›Full record

ArticleOncology letters2018

miR-329 inhibits papillary thyroid cancer progression via direct targeting WNT1.

Liang Wu, Fulai Pei, Xiaojuan Men, Kai Wang, Deliang Ma

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. The Changing Face ofFrontiers in surgery · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Liang WuDepartment of Oncology, Linyi Central Hospital, Linyi, Shandong 276400, P.R. China.
Fulai PeiDepartment of Oncology, Linyi Central Hospital, Linyi, Shandong 276400, P.R. China.
Xiaojuan MenDepartment of Breast Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
Kai WangDepartment of Breast Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China.
Deliang MaDepartment of Oncology, Linyi Central Hospital, Linyi, Shandong 276400, P.R. China.
Linyi People's Hospital · CNWeifang People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulated microRNA-329 (miR-329) serves an important role in the progression of certain types of tumor. However, the exact function and mechanisms of miR-329 in papillary thyroid cancer (PTC) remain unknown. The present study investigated the function and mechanisms of miR-329 in regulating PTC cell progression. The results revealed that the expression of miR-329 was significantly downregulated in PTC tissues and cell lines compared with adjacent normal tissues and a human immortalized follicular cell line. miR-329 mimics notably decreased PTC cell proliferation, colony formation and WNT1 expression

Indexed as

microRNA-329migration and invasionpapillary thyroid cancerproliferationWNT1

Identifiers

PMID30127962
PMCPMC6096240
OpenAlexW2812300083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.