Simultaneous Determination of Ascorbic Acid, Uric Acid and Tryptophan by Novel Carbon Nanotube Paste Electrode.

Mohammad Mazloum-Ardakani, Mahboobe Abolhasani-Soorki, Alireza Khoshroo, Fariba Sabaghian, Bibi-Fatemeh Mirjalili

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Article in Iranian journal of pharmaceutical research : IJPR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Mohammad Mazloum-ArdakaniDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.

Mahboobe Abolhasani-SoorkiDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.

Alireza KhoshrooDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.

Fariba SabaghianDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.

Bibi-Fatemeh MirjaliliDepartment of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present paper, electrochemical methods were used to investigate the behavior of ascorbic acid at a carbon paste electrode modified with 2,2'-((1E)-(1,2 phenylenebis(azanylylidene)) bis(methanylylidene))bis(benzene-1,4-diol) (PBD) and oxidized multiwall carbon nanotubes. The modified carbon paste electrode showed high electrocatalytic activity toward ascorbic acid; the current was enhanced significantly relative to the situation prevailing when an unmodified carbon paste electrode was used. Cyclic voltammetry was used to investigate the redox properties of this modified electrode at various solution pH values and at various scan rates. Using differential pulse voltammetry, the calibration curves for AA were obtained over the range of 1.0-80.0 and 80-4000.0 μM, respectively. The detection limit was 0.3 μM. The present method provides a simple method for selective detection of ascorbic acid. DPV also was used for simultaneous determination of AA, uric acid, and tryptophan at the modified electrode. Finally, the proposed electrochemical sensor was used for determinations of these substances in in biological systems and pharmaceutical samples.

Indexed as

Ascorbic acidCarbon nanotubeSensorTryptophanUric Acid

Identifiers

PMID30127810

PMCPMC6094440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.