Evidence map›Paper›PMID 30127785›Full record

ArticleFrontiers in immunology2018

Determination of a Predictive Cleavage Motif for Eluted Major Histocompatibility Complex Class II Ligands.

Sinu Paul, Edita Karosiene, Sandeep Kumar Dhanda, Vanessa Jurtz, Lindy Edwards, Morten Nielsen, Alessandro Sette, Bjoern Peters

Open access · goldAbstract readValidation Study
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Immunopeptidomics ofBiology · 2024
    Article
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  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Structural Prediction of Peptide-MHC Binding Modes.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Sinu PaulDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Edita KarosieneDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Sandeep Kumar DhandaDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Vanessa JurtzDepartment of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.
Lindy EdwardsDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Morten NielsenDepartment of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Bjoern PetersDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
La Jolla Institute for Immunology · USTechnical University of Denmark · DK

Funding

NIAID NIH HHS HHSN272201200010C
6 · The paper itself

Abstract

CD4

Indexed as

AlgorithmsAntigen PresentationAmino Acid MotifsAmino AcidsBinding SitesCD4-Positive T-LymphocytesDatabases, ProteinDatasets as TopicEpitopes, T-LymphocyteHistocompatibility Antigens Class IIHumansLigandsMass SpectrometryPeptidesProtein BindingProteolysisAmino AcidsEpitopes, T-LymphocyteHistocompatibility Antigens Class IILigandsPeptidesantigen processingCD4+ T cell epitopesepitope predictionhuman leukocyte antigenligand elutionmajor histocompatibility complex class IInatural cleavage motif

Identifiers

PMID30127785
PMCPMC6087742
OpenAlexW2886770018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.