Evidence map›Paper›PMID 30127744›Full record

ArticleFrontiers in pharmacology2018

Blockade of Pannexin-1 Channels and Purinergic P2X7 Receptors Shows Protective Effects Against Cytokines-Induced Colitis of Human Colonic Mucosa.

Erica F Diezmos, Irit Markus, D S Perera, Steven Gan, Li Zhang, Shaun L Sandow, Paul P Bertrand, Lu Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Novel Naphthyridones Targeting Pannexin 1 for Colitis Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 andInternational journal of molecular sciences · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Mechanisms of Connexin Regulating Peptides.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Erica F DiezmosDepartment of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
Irit MarkusDepartment of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
D S PereraSydney Colorectal Associates, Hurstville, NSW, Australia.
Steven GanSydney Colorectal Associates, Hurstville, NSW, Australia.
Li ZhangSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.
Shaun L SandowDepartment of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
Paul P BertrandDepartment of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
Lu LiuDepartment of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
UNSW Sydney · AUUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

colonic inflammationhuman colitisP2X7 receptorpannexin-1tissue explants

Identifiers

PMID30127744
PMCPMC6087744
OpenAlexW2885916579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.