ArticleBMC ear, nose, and throat disorders2018
Odontogenic necrotizing fasciitis: a systematic review of the literature.
Article in BMC ear, nose, and throat disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 62 citations in OpenAlex.
- Vacuum-Assisted Closure-Assisted Reconstruction of Extensive Anterior Cervical Necrotizing Fasciitis: A Case Report.Cureus · 2026Article
- Necrotising fasciitis of the neck, chest and abdomen arising from odontogenic Ludwig's angina in a healthy young adult.BMJ case reports · 2026Article
- Explainable machine learning differentiates necrotizing fasciitis and osteomyelitis via routine blood biomarkers.NPJ digital medicine · 2026Article
- Admission prognostic nutritional index predicts prolonged hospitalization in severe odontogenic deep neck infections.Odontology · 2026Article
- Article
- Extensive Odontogenic Deep Neck Infection Complicated by Necrotizing Fasciitis and Bilateral Mastitis: A Rare Case Report.Case reports in surgery · 2026Article
- Wide exposure VS. stab surgical incisions in necrotizing fasciitis of the head and neck: a retrospective analysis of 22 cases.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Oral pathologic conditions and impaired cytokine response in patients with previous cerebral abscess or cervical necrotizing soft tissue infection.Frontiers in cellular and infection microbiology · 2025Observational
- Necrotizing fasciitis of the head and neck - clinical features, diagnostics, and management strategies.Oncoscience · 2025Article
- Critical Chest Wall Necrotizing Fasciitis Triggered by Herpes Zoster: A Case Report.The American journal of case reports · 2024Article
- Atypical presentation of polymicrobial cervicofacial necrotizing fasciitis: An extraordinary odontogenic infection in a healthy female patient.Clinical case reports · 2024Article
- Efficacity of hyperbaric oxygen therapy for necrotizing fasciitis in the maxillofacial region: The review of the literature.International wound journal · 2024Review
- Article
- Serious Complications and Treatment Strategies Associated with Odontogenic Infections.The Eurasian journal of medicine · 2023Article
- Case Report of Gas Gangrene after Reconstructive Surgery with Anterolateral Thigh Flap for Resection of Oral Cancer.Plastic and reconstructive surgery. Global open · 2023Article
- Pediatric Cervicofacial Necrotizing Fasciitis-A Challenge for a Medical Team.Children (Basel, Switzerland) · 2023Article
- Survival rate of odontogenic descending necrotizing mediastinitis. Our experience in last 5 years.Medicina oral, patologia oral y cirugia bucal · 2023Article
- Review
- Early diagnosis of craniofacial necrotising fasciitis: Analysis of clinical risk factors.International wound journal · 2022Article
- A Severe Case of Odontogenic Infection and Necrotizing Fasciitis of the Anterior Chest Wall and Neck.Cureus · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile odontogenic soft tissue infections of the head and neck are common, progression to necrotizing fasciitis is relatively rare. Necrotizing fasciitis is a potentially life-threatening and rapidly progressive soft tissue infection that can lead to significant skin and soft tissue loss, mediastinitis, vascular thrombosis or rupture, limb loss, organ failure, and death.
methodsA PubMed literature search was conducted for case reports and case series on odontogenic necrotizing fasciitis. Individual patient data was analyzed and compiled and demographic, treatment, microbiology, and mortality data were extracted. Fisher's exact test was used to examine the relationship between death from odontogenic necrotizing fasciitis and diabetes mellitus (DM) and human immunodeficiency virus (HIV) positivity.
resultsA total of 58 studies totaling 164 patients were identified. Thirty-three patients had DM and 3 were HIV +. All patients underwent aggressive surgical debridement and treatment with IV antibiotics. Twenty patients were also treated with hyperbaric oxygen. There were 16 deaths reported, for a mortality rate of 9.8%. The mortality rate among patients with DM was 30.3 and 0% among HIV positive patients. There was a statistically significant increase in the mortality rate in DM patients with odontogenic necrotizing fasciitis (
conclusionsNecrotizing fasciitis arising from odontogenic infection is a rapidly progressive and life-threatening illness. Prompt recognition of the infection, aggressive and often serial surgical debridement, and aggressive broad-spectrum antibiotics are necessary to prevent serious morbidity and mortality. Patients with diabetes mellitus are at a significantly increased risk of death from odontogenic necrotizing fasciitis.
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