ArticleOncoTargets and therapy2018
miR-497 inhibited proliferation, migration and invasion of thyroid papillary carcinoma cells by negatively regulating YAP1 expression.
Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Comparative epigenomics to clinical trials in human breast cancer and canine mammary tumor.Animal cells and systems · 2025Review
- MiR-590 suppresses the progression of non-small cell lung cancer by regulating YAP1 and Wnt/β-catenin signaling.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022Article
- miR-497 inhibits proliferation and invasion in triple-negative breast cancer cells via YAP1.Oncology letters · 2021Article
- Regulation of microRNA-497 expression in human cancer.Oncology letters · 2021Review
- Immortalization up-regulated protein promotes tumorigenesis and inhibits apoptosis of papillary thyroid cancer.Journal of cellular and molecular medicine · 2020Article
- Article
- LINC00473 contributes to the radioresistance of esophageal squamous cell carcinoma by regulating microRNA‑497‑5p and cell division cycle 25A.International journal of molecular medicine · 2020Article
- H3K27ac-activated LINC00519 promotes lung squamous cell carcinoma progression by targeting miR-450b-5p/miR-515-5p/YAP1 axis.Cell proliferation · 2020Article
- Screening of key miRNAs and evaluation of their diagnostic and prognostic values in nasopharyngeal carcinoma.Oncology letters · 2019Article
- Tanshinol inhibits the growth, migration and invasion of hepatocellular carcinoma cells via regulating the PI3K-AKT signaling pathway.OncoTargets and therapy · 2019Article
- MicroRNA-497-5p Induces Cell Cycle Arrest Of Cervical Cancer Cells In S Phase By Targeting CBX4.OncoTargets and therapy · 2019Article
- LncRNA SNHG16 drives proliferation and invasion of papillary thyroid cancer through modulation of miR-497.OncoTargets and therapy · 2019Article
Corrections and comments
- Retraction · 2023-01-19Duplication of/in Image · Original Data and/or Images not Provided and/or not Available ·
- Retracted
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis article aimed to investigate the effect of miR-497 on thyroid papillary carcinoma. MATERIALS AND
methodsmiR-497 expression was analyzed using The Cancer Genome Atlas. A total of 56 papillary thyroid carcinoma patients' tumor tissues and normal tissues were collected. Nthy-ori 3-1 and K1 cells were cultured. K1 cells were also transfected. Quantitative real-time polymerase chain reaction and Western blot were used to detect miR-497 and yes-associated protein 1 (YAP1) expression. Luciferase reporter assay was performed. MTT and Transwell assay were conducted to measure cells' proliferation, migration and invasion. Immunofluorescence detection was used to detect YAP1-positive cells.
resultsmiR-497 was downregulated, while YAP1 was upregulated in thyroid papillary carcinoma tissues and K1 cells (
conclusionmiR-497 regulated the proliferation, migration and invasion of K1 cells by negatively regulating YAP1 expression.
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