Evidence map›Paper›PMID 30127295›Full record

ArticleBiomolecules2018

Novel DNA Methylation Sites Influence

Tina Haase, Christian Müller, Julia Krause, Caroline Röthemeier, Justus Stenzig, Sonja Kunze, Melanie Waldenberger, Thomas Münzel, Norbert Pfeiffer, Philipp S Wild and 6 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. The Role of GPR15 Function in Blood and Vasculature.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Tina HaaseClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. t.haase@uke.de.
Christian MüllerClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. ch.mueller@uke.de.
Julia KrauseClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. j.krause@uke.de.
Caroline RöthemeierClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. roethemeierC@rki.de.
Justus StenzigGerman Centre for Cardiovascular Research (DZHK), 13316 Berlin, Germany. j.stenzig@uke.de.
Sonja KunzeResearch Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany. sonja.kunze@helmholtz-muenchen.de.
Melanie WaldenbergerGerman Centre for Cardiovascular Research (DZHK), 13316 Berlin, Germany. waldenberger@helmholtz-muenchen.de.
Thomas MünzelGerman Centre for Cardiovascular Research (DZHK), 13316 Berlin, Germany. tmuenzel@uni-mainz.de.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. norbert.pfeiffer@unimedizin-mainz.de.
Philipp S WildGerman Centre for Cardiovascular Research (DZHK), 13316 Berlin, Germany. philipp.wild@unimedizin-mainz.de.
Matthias MichalDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany. Matthias.Michal@unimedizin-mainz.de.
Federico MariniUniversity Medical Center, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), 55131 Mainz, Germany. marinif@uni-mainz.de.ORCID 0000-0003-3252-7758
Mahir KarakasClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. m.karakas@uke.de.
Karl J LacknerGerman Centre for Cardiovascular Research (DZHK), 13316 Berlin, Germany. Karl.Lackner@unimedizin-mainz.de.
Stefan BlankenbergClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. s.blankenberg@uke.de.
Tanja ZellerClinic for General and Interventional Cardiology, University Heart Center Hamburg, 20246 Hamburg, Germany. t.zeller@uke.de.
Universität Hamburg · DEJohannes Gutenberg University Mainz · DEHelmholtz Zentrum München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking is a major risk factor for cardiovascular diseases and has been implicated in the regulation of the G protein-coupled receptor 15 (GPR15) by affecting CpG methylation. The G protein-coupled receptor 15 is involved in angiogenesis and inflammation. An effect on

Indexed as

AgedDNA MethylationFemaleGene Expression RegulationGenetic LociHumansMaleMiddle AgedReceptors, G-Protein-CoupledReceptors, PeptideRNA, MessengerSmokingGPR15 protein, humanReceptors, G-Protein-CoupledReceptors, PeptideRNA, MessengerbiomarkerDNA methylationGPR15smoking

Identifiers

PMID30127295
PMCPMC6163736
OpenAlexW2886351769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.