Evidence map›Paper›PMID 30127286›Full record

ArticleViruses2018

The Morphology and Assembly of Respiratory Syncytial Virus Revealed by Cryo-Electron Tomography.

Zunlong Ke, Rebecca S Dillard, Tatiana Chirkova, Fredrick Leon, Christopher C Stobart, Cheri M Hampton, Joshua D Strauss, Devi Rajan, Christina A Rostad, Jeannette V Taylor and 9 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 95 citations in OpenAlex.

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  15. Implications of morphological variation in influenza viruses.Microbiology and molecular biology reviews : MMBR · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Zunlong KeDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. zunlongke@gatech.edu.ORCID 0000-0002-8408-850X
Rebecca S DillardDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. rebecca.s.dillard@emory.edu.
Tatiana ChirkovaDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. tania.chirkova@emory.edu.
Fredrick LeonDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. fredrick.leon@emory.edu.
Christopher C StobartDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. cstobart@butler.edu.
Cheri M HamptonDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. cheri.hampton.ctr@us.af.mil.ORCID 0000-0003-0069-8712
Joshua D StraussDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. joshua.d.strauss@emory.edu.
Devi RajanDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. drajan@emory.edu.
Christina A RostadDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. christina.rostad@emory.edu.
Jeannette V TaylorRobert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, GA 30322, USA. jvtaylo@emory.edu.
Hong YiRobert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, GA 30322, USA. hyi@emory.edu.
Raven ShahDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. raven.shah@emory.edu.
Mengtian JinDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. mengtian.jin@emory.edu.
Tina V HartertDivision of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. tina.hartert@Vanderbilt.Edu.
R Stokes PeeblesDivision of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. stokes.peebles@Vanderbilt.Edu.
Barney S GrahamVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. bgraham@mail.nih.gov.
Martin L MooreDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. mlmoor2@emory.edu.
Larry J AndersonDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. larry.anderson@emory.edu.
Elizabeth R WrightDivision of Pediatric Infectious Diseases, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA. erwright2@wisc.edu.ORCID 0000-0003-0712-9475
Emory University · USVanderbilt University · USGeorgia Institute of Technology · USNational Institutes of Health · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Viral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tina V Hartert · 2011 to 2026
$34.9M
Training a New Generation of VaccinologistsT32AI074492 · NIAID · EMORY UNIVERSITY · PI Rama Rao Amara, Benjamin A Lopman · 2009 to 2026
$6.4M
Training Program in Biochemistry, Cell and Molecular BiologyT32GM008367 · NIGMS · EMORY UNIVERSITY · PI BOISE, LAWRENCE H., CORBETT, ANITA H. · 1990 to 2019
$5.6M
Atlanta Pediatric Scholars ProgramK12HD072245 · NICHD · EMORY UNIVERSITY · PI Shari Barkin · 2012 to 2026
$5.5M
PGI2 regulation of TSLP-mediated allergic inflammation in the lungR01AI111820 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEBLES, RAY STOKES · 2014 to 2018
$2.0M
Role of the Respiratory Syncytial Virus Fusion Protein in Airway Mucus InductionR01AI087798 · NIAID · EMORY UNIVERSITY · PI MOORE, MARTIN LAWRENCE · 2010 to 2014
$1.9M
Structural Investigations Of Macromolecular Complexes Critical To hRSV Life CycleR01GM114561 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SANTANGELO, PHILIP J, WRIGHT, ELIZABETH R · 2016 to 2019
$1.6M
Structural studies of respiratory syncytial virusR21AI101775 · NIAID · EMORY UNIVERSITY · PI WRIGHT, ELIZABETH R · 2013 to 2014
$429k
Structural analysis of tetherin-mediated HIV restrictionF32GM112517 · NIGMS · EMORY UNIVERSITY · PI STRAUSS, JOSHUA · 2014 to 2015
$106k
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI087798NIAID NIH HHS R01 AI111820NIAID NIH HHS R21 AI101775NIAID NIH HHS T32 AI074492NIAID NIH HHS U19 AI095227NICHD NIH HHS K12 HD072245NIGMS NIH HHS F32 GM112517NIGMS NIH HHS R01 GM114561NIGMS NIH HHS T32 GM008367
6 · The paper itself

Abstract

Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract disease in young children. With repeat infections throughout life, it can also cause substantial disease in the elderly and in adults with compromised cardiac, pulmonary and immune systems. RSV is a pleomorphic enveloped RNA virus in the

Indexed as

A549 CellsAnimalsBronchiCell LineChlorocebus aethiopsCryoelectron MicroscopyElectron Microscope TomographyEpithelial CellsHeLa CellsHumansMicrotomyRespiratory Syncytial Virus, HumanVero CellsVirionVirus Assemblycryo-electron microscopy (cryo-EM)cryo-electron tomography (cryo-ET)enveloped virushuman respiratory syncytial virus (RSV)viral morphogenesisvirus assembly

Identifiers

PMID30127286
PMCPMC6116276
OpenAlexW2888589836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.