Evidence map›Paper›PMID 30127254›Full record

ReviewToxins2018

Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein.

Wei-Wei Shi, Kam-Bo Wong, Pang-Chui Shaw

Abstract readReview
In one paragraph

Review in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Toxic proteins application in cancer therapy.Molecular biology reports · 2021
    Review
  10. Review
  11. Advances on Tumor-Targeting Delivery of Cytotoxic Proteins.ACS pharmacology & translational science · 2020
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei-Wei ShiCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Sha Tin New Town, Hong Kong, China. Shiww@cuhk.edu.hk.
Kam-Bo WongCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Sha Tin New Town, Hong Kong, China. kbwong@cuhk.edu.hk.
Pang-Chui ShawCentre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Sha Tin New Town, Hong Kong, China. pcshaw@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichosanthin (TCS) is an RNA

Indexed as

Antineoplastic AgentsAntiviral AgentsImmunologic FactorsTrichosanthinAnimalsHumansProtein ConformationAntineoplastic AgentsAntiviral AgentsImmunologic FactorsTrichosanthinmechanismmultiple pharmacological activitiesribosomal stalk P proteinribosome-inactivating proteinTCS

Identifiers

PMID30127254
PMCPMC6115768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.