Evidence map›Paper›PMID 30127237›Full record

ArticlePathogens (Basel, Switzerland)2018

Preliminary Studies on Immune Response and Viral Pathogenesis of Zika Virus in Rhesus Macaques.

Shawna M Woollard, Omalla A Olwenyi, Debashis Dutta, Rajnish S Dave, Saumi Mathews, Santhi Gorantla, Noel Johnson, Luis Giavedoni, Robert B Norgren, Siddappa N Byrareddy

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Shawna M WoollardDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. shawnamwoollard@gmail.com.
Omalla A OlwenyiDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. omalla.olwenyi@unmc.edu.
Debashis DuttaDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. debashis.dutta@unmc.edu.
Rajnish S DaveDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. raj.dave@unmc.edu.
Saumi MathewsDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. saumi.mathews@unmc.edu.ORCID 0000-0002-1110-9656
Santhi GorantlaDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. sgorantla@unmc.edu.
Noel JohnsonDepartment of Comparative Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA. ndjohnso@unmc.edu.
Luis GiavedoniDepartment of Virology & Immunology, Texas Biomedical Research Institute, San Antonio, TX 78245, USA. lgiavedoni@TxBiomed.org.ORCID 0000-0001-5244-7187
Robert B NorgrenDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198-5805, USA. rnorgren@unmc.edu.
Siddappa N ByrareddyDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. sid.byrareddy@unmc.edu.ORCID 0000-0002-6889-4640
University of Nebraska Medical Center · USTexas Biomedical Research Institute · US

Funding

Role of HIV Env glycosylation in mucosal transmissionR01AI113883 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BYRAREDDY, SIDDAPPA N · 2014 to 2018
$3.9M
NIAID NIH HHS R01 AI113883
6 · The paper itself

Abstract

Zika Virus (ZIKV) is primarily transmitted through mosquito bites. It can also be transmitted during sexual intercourse and in utero from mother to fetus. To gain preliminary insight into ZIKV pathology and immune responses on route of transmission, rhesus macaques (RMs) were inoculated with ZIKV (PRVABC59) via intravaginal (IVAG) (

Indexed as

Flavivirusesimmunopathogenesisintravaginalrhesus macaquesexual transmissionZika

Identifiers

PMID30127237
PMCPMC6160936
OpenAlexW2886117421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.