Evidence map›Paper›PMID 30127117›Full record

ArticleNeural regeneration research2018

Aminooxyacetic acid improves learning and memory in a rat model of chronic alcoholism.

Ai-Lin Du, Hao-Zhi Qin, Hong-Bo Jiang, Peng-Yan Fu, Ke Lou, Yu-Ming Xu

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  3. Role of cystathionine-β-synthase and hydrogen sulfide in down syndrome.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ai-Lin DuDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province; Department of Physiology and Neurobiology, Xinxiang Medical University, Henan Provincial Key Laboratory of Brain Research, Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan Province, China.
Hao-Zhi QinDepartment of Physiology and Neurobiology, Xinxiang Medical University, Henan Provincial Key Laboratory of Brain Research, Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan Province, China.
Hong-Bo JiangDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou; Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan Province, China.
Peng-Yan FuDepartment of Physiology and Neurobiology, Xinxiang Medical University, Henan Provincial Key Laboratory of Brain Research, Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan Province, China.
Ke LouDepartment of Physiology and Neurobiology, Xinxiang Medical University, Henan Provincial Key Laboratory of Brain Research, Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan Province, China.
Yu-Ming XuDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Xinxiang Medical University · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic alcoholism seriously damages the central nervous system and leads to impaired learning and memory. Cell damage in chronic alcoholism is strongly associated with elevated levels of hydrogen sulfide (H

Indexed as

aminooxyacetic acidATP enzyme activitybrain injuryCa2+ overloadchronic alcoholism rat modelhydrogen sulfidelearning and memory abilitiesmitochondriaMorris water mazemyelin basic proteinnerve regenerationneural regeneration

Identifiers

PMID30127117
PMCPMC6126113
OpenAlexW2886024080

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.