Evidence map›Paper›PMID 30127087›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

The PGI

Weisong Zhou, Jian Zhang, Shinji Toki, Kasia Goleniewska, Marc O Johnson, Melissa H Bloodworth, Dawn C Newcomb, R Stokes Peebles

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Prostaglandin IThe Journal of allergy and clinical immunology · 2025
    Article
  2. [Expression of prostacyclin receptor in chronic rhinosinusitis and its relationship with type 2 inflammation].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
  3. Article
  4. Endogenous inhibitory mechanisms in asthma.The journal of allergy and clinical immunology. Global · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Prostaglandin IDNA and cell biology · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Weisong ZhouDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and weisong.zhou@vanderbilt.edu.ORCID 0000-0002-4419-2302
Jian ZhangDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.
Shinji TokiDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.ORCID 0000-0003-4379-9118
Kasia GoleniewskaDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.
Marc O JohnsonDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232.
Melissa H BloodworthDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.
Dawn C NewcombDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.
R Stokes PeeblesDivision of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232; and.ORCID 0000-0002-1429-7875
Vanderbilt University · US

Funding

Viral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Dawn C Newcomb · 2011 to 2026
$34.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
PGI2 regulation of TSLP-mediated allergic inflammation in the lungR01AI111820 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEBLES, RAY STOKES · 2014 to 2018
$2.0M
The Role of PGI2 in Allergic InflammationR01HL090664 · NHLBI · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 2009 to 2013
$1.9M
Prostacyclin (PGI2) Regulation of RSV-induced IllnessR01AI054660 · NIAID · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 2003 to 2007
$1.7M
COX Regulation of Allergic Sensitization and Immune Memory GenerationR56AI076411 · NIAID · VANDERBILT UNIVERSITY · PI ZHOU, WEISONG · 2009 to 2009
$388k
Exogenous PGI2 protection against RSV-induced illnessF30AI118376 · NIAID · VANDERBILT UNIVERSITY · PI BLOODWORTH, MELISSA H. · 2015 to 2019
$152k
PGI2 regulation of CD4+ Th2 metabolism in allergic airway inflammationI01BX004299 · VA · VETERANS HEALTH ADMINISTRATION · PI PEEBLES, RAY STOKES · 2019 to 2025
–
The role of cyclooxygenase in the adaptive immune response and toleranceI01BX000624 · VA · VETERANS HEALTH ADMINISTRATION · PI PEEBLES, RAY STOKES · 2009 to 2019
–
BLRD VA I01 BX000624BLRD VA I01 BX004299NHLBI NIH HHS R01 HL090664NIAID NIH HHS F30 AI118376NIAID NIH HHS R01 AI054660NIAID NIH HHS R01 AI111820NIAID NIH HHS R56 AI076411NIAID NIH HHS U19 AI095227NIGMS NIH HHS T32 GM007347
6 · The paper itself

Abstract

IL-33 has pleiotropic functions in immune responses and promotes the development of allergic diseases and asthma. IL-33 induces Th2 differentiation and enhances type 2 cytokine production by CD4

Indexed as

AlternariaAlternariosisAnimalsCell DifferentiationCells, CulturedEpoprostenolInterleukin-2Interleukin-2 Receptor alpha SubunitInterleukin-33LungLymphocyte ActivationMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutReceptors, ProstaglandincicaprostEpoprostenolInterleukin-2Interleukin-2 Receptor alpha SubunitInterleukin-33Receptors, Prostaglandin

Identifiers

PMID30127087
PMCPMC6162094
OpenAlexW2888768629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.