Evidence map›Paper›PMID 30127032›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins.

Haijia Yu, Chong Shen, Yinghui Liu, Bridget L Menasche, Yan Ouyang, Michael H B Stowell, Jingshi Shen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. ELAPOR1 is a copper-dependent tethering factor driving proacrosomal vesicle fusion during acrosome biogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. The role of syntaxins in retinal function and health.Frontiers in cellular neuroscience · 2024
    Review
  6. Article
  7. Article
  8. Faithful SM proteins chaperone SNAREs on path to successful assembly.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Energetics, kinetics, and pathways of SNARE assembly in membrane fusion.Critical reviews in biochemistry and molecular biology · 2022
    Review
  14. The function of VAMP2 in mediating membrane fusion: An overview.Frontiers in molecular neuroscience · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Haijia YuJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, 210023 Nanjing, China.
Chong ShenDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.
Yinghui LiuJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, 210023 Nanjing, China.
Bridget L MenascheDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.
Yan OuyangDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.
Michael H B StowellDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309; michael.stowell@colorado.edu jingshi.shen@colorado.edu.ORCID 0000-0001-7250-1419
Jingshi ShenDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309; michael.stowell@colorado.edu jingshi.shen@colorado.edu.
University of Colorado Boulder · USNanjing Normal University · CN

Funding

TRAINING IN SIGNAL TRANSDUCTION &CELL CYCLE REGULATIONT32GM008759 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI AHN, NATALIE G. · 2000 to 2020
$5.9M
Predoctoral Training Program in Signaling and Cellular Regulation INCLUDE Down Syndrome SupplementT32GM142607 · NIGMS · UNIVERSITY OF COLORADO · PI Sabrina Leigh Spencer, Tin Tin Su · 2021 to 2026
$3.6M
Protein-membrane interactions in regulated exocytosisR35GM126960 · NIGMS · UNIVERSITY OF COLORADO · PI Jingshi Shen · 2018 to 2026
$3.2M
Regulatory Mechanisms of GLUT4 ExocytosisR01DK095367 · NIDDK · UNIVERSITY OF COLORADO · PI SHEN, JINGSHI · 2013 to 2017
$1.7M
Membrane Protein Polyhedral Nanoparticles for High Resolution Structure/Function StudiesR01GM114496 · NIGMS · UNIVERSITY OF COLORADO · PI STOWELL, MICHAEL H. B. · 2015 to 2016
$607k
Regulatory Mechanisms of GLUT4 ExocytosisR56DK095367 · NIDDK · UNIVERSITY OF COLORADO · PI SHEN, JINGSHI · 2012 to 2018
$598k
NIDDK NIH HHS R01 DK095367NIDDK NIH HHS R56 DK095367NIGMS NIH HHS R01 GM114496NIGMS NIH HHS R35 GM126960NIGMS NIH HHS T32 GM008759NIGMS NIH HHS T32 GM142607
6 · The paper itself

Abstract

Soluble

Indexed as

Munc18 ProteinsPeptidesSNARE ProteinsAnimalsChlorocebus aethiopsCOS CellsExocytosisKineticsMembrane FusionMiceRatsMunc18 ProteinsPeptidesSNARE ProteinsStxbp1 protein, ratStxbp2 protein, mouseexocytosismembrane fusionSM proteinSNAREvesicle fusion

Identifiers

PMID30127032
PMCPMC6130351
OpenAlexW2888333487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.