Evidence map›Paper›PMID 30127026›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Intestinal host defense outcome is dictated by PGE

Naiara Naiana Dejani, Allan Botinhon Orlando, Victoria Eugenia Niño, Letícia de Aquino Penteado, Felipe Fortino Verdan, Júlia Miranda Ribeiro Bazzano, Ana Campos Codo, Ana Carolina Guerta Salina, Amanda Correia Saraiva, Matheus Rossi Avelar and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Different bacterial cargo in apoptotic cells drive distinct macrophage phenotypes.Apoptosis : an international journal on programmed cell death · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Concentrations of PGEPathogens (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Efferocytosis and Its Role in Inflammatory Disorders.Frontiers in cell and developmental biology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Naiara Naiana DejaniDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Allan Botinhon OrlandoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Victoria Eugenia NiñoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Letícia de Aquino PenteadoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Felipe Fortino VerdanDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Júlia Miranda Ribeiro BazzanoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Ana Campos CodoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Ana Carolina Guerta SalinaDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Amanda Correia SaraivaDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Matheus Rossi AvelarDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
Luis Carlos SpolidorioDepartment of Physiology and Pathology, School of Dentistry, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil.
C Henrique SerezaniDepartment of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0002-5363-415X
Alexandra Ivo MedeirosDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University, Araraquara, 01049-010 São Paulo, Brazil; medeirosai@fcfar.unesp.br.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory responses are terminated by the clearance of dead cells, a process termed efferocytosis. A consequence of efferocytosis is the synthesis of the antiinflammatory mediators TGF-β, PGE

Indexed as

AnimalsCitrobacter rodentiumColitisDendritic CellsDinoprostoneEnterobacteriaceae InfectionsFemaleIntestinesMacrophagesMiceReceptors, Prostaglandin E, EP4 SubtypeDinoprostonePtger4 protein, mouseReceptors, Prostaglandin E, EP4 SubtypeefferocytosisEP4infected apoptotic cellsprostaglandin E2Th17 cells

Identifiers

PMID30127026
PMCPMC6130380
OpenAlexW2888185853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.