Evidence map›Paper›PMID 30127013›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Bacterial symbionts use a type VI secretion system to eliminate competitors in their natural host.

Lauren Speare, Andrew G Cecere, Kirsten R Guckes, Stephanie Smith, Michael S Wollenberg, Mark J Mandel, Tim Miyashiro, Alecia N Septer

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

  1. Article
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  11. Applied and environmental microbiology · 2025
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  17. Review
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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lauren SpeareDepartment of Marine Sciences, University of North Carolina, Chapel Hill, NC 27599.
Andrew G CecereDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802.
Kirsten R GuckesDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802.
Stephanie SmithDepartment of Marine Sciences, University of North Carolina, Chapel Hill, NC 27599.
Michael S WollenbergDepartment of Biology, Kalamazoo College, Kalamazoo, MI 49006.
Mark J MandelDepartment of Medical Microbiology & Immunology, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0001-6506-6711
Tim MiyashiroDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802; tim14@psu.edu asepter@email.unc.edu.
Alecia N SepterDepartment of Marine Sciences, University of North Carolina, Chapel Hill, NC 27599; tim14@psu.edu asepter@email.unc.edu.

Funding

Genetic Analysis of Beneficial Bacterial ColonizationR35GM119627 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MANDEL, MARK J · 2016 to 2021
$2.2M
Analysis of quorum-signaling crosstalk within the squid-vibrio symbiosisR00GM097032 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MIYASHIRO, TIMOTHY · 2013 to 2015
$743k
Regulation of Bacterial Aggregation During Host ColonizationR21AI117262 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI MANDEL, MARK J · 2016 to 2017
$408k
NIAID NIH HHS R21 AI117262NIGMS NIH HHS R00 GM097032NIGMS NIH HHS R35 GM119627
6 · The paper itself

Abstract

Intraspecific competition describes the negative interaction that occurs when different populations of the same species attempt to fill the same niche. Such competition is predicted to occur among host-associated bacteria but has been challenging to study in natural biological systems. Although many bioluminescent

Indexed as

Type IV Secretion SystemsAliivibrio fischeriAnimalsDecapodiformesSymbiosisType IV Secretion SystemsAliivibrio fischeriEuprymna scolopessquidsymbiosistype VI secretion

Identifiers

PMID30127013
PMCPMC6130350

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.