Evidence map›Paper›PMID 30126994›Full record

Trial reportProceedings of the National Academy of Sciences of the United States of America2018

Enterotoxigenic

Alexander A Crofts, Simone M Giovanetti, Erica J Rubin, Frédéric M Poly, Ramiro L Gutiérrez, Kawsar R Talaat, Chad K Porter, Mark S Riddle, Barbara DeNearing, Jessica Brubaker and 7 more

Open access · bronzeAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. High Efficacy of Rose Bengal in Reducing the Pathogenicity ofInternational journal of microbiology · 2025
    Article
  13. Article
  14. Inhibitory Effect ofMicroorganisms · 2024
    Article
  15. Current understandings of colibactin regulation.Microbiology (Reading, England) · 2024
    Review
  16. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Emergence of colistin-resistant hypervirulentEmerging microbes & infections · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Alexander A CroftsDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
Simone M GiovanettiDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
Erica J RubinDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
Frédéric M PolyEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Ramiro L GutiérrezEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Kawsar R TalaatDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Chad K PorterEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Mark S RiddleEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Barbara DeNearingDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Jessica BrubakerDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Milton MacielImmunology, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817.
Ashley N AlcalaEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Subhra ChakrabortyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Michael G ProutyEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Stephen J SavarinoEnteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910.
Bryan W DaviesDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
M Stephen TrentDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602; strent@uga.edu.ORCID 0000-0001-6134-1800
Naval Medical Research Command · USJohns Hopkins University · USThe University of Texas at Austin · USHenry M. Jackson Foundation · USUniversity of Georgia · US

Funding

MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESR01AI064184 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2006 to 2015
$3.4M
The Outer Surface of Vibrio CholeraeR01AI076322 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2008 to 2017
$3.2M
The Outer Surface of Vibrio choleraeR56AI076322 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2013 to 2013
$384k
NIAID NIH HHS R01 AI064184NIAID NIH HHS R01 AI076322NIAID NIH HHS R56 AI076322
6 · The paper itself

Abstract

Enterotoxigenic

Indexed as

Gene Expression Regulation, BacterialAdultBiofilmsDiarrheaEnterotoxigenic Escherichia coliEpithelial CellsEscherichia coli InfectionsEscherichia coli ProteinsEscherichia coli VaccinesFemaleHealthy VolunteersHost-Pathogen InteractionsHumansIntestinesIron-Sulfur ProteinsMaleEscherichia coli ProteinsEscherichia coli VaccinesFNR protein, E coliIron-Sulfur ProteinsVirulence Factorscfaenterotoxigenic E. coliETECFNRtoxin

Identifiers

PMID30126994
PMCPMC6156659
OpenAlexW2888272762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.