Evidence map›Paper›PMID 30126962›Full record

ArticleAntimicrobial agents and chemotherapy2018

Carbapenem Resistance Caused by High-Level Expression of OXA-663 β-Lactamase in an OmpK36-Deficient Klebsiella pneumoniae Clinical Isolate.

Peijun Ma, Hannah H Laibinis, Christoph M Ernst, Deborah T Hung

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Peijun MaThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Hannah H LaibinisThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Christoph M ErnstThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Deborah T HungThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA hung@molbio.mgh.harvard.edu.ORCID 0000-0003-4262-0673
Broad Institute · US

Funding

RNA based diagnostics for rapid pathogen identification and drug resistanceR01AI117043 · NIAID · BROAD INSTITUTE, INC. · PI HUNG, DEBORAH T · 2015 to 2019
$6.5M
NIAID NIH HHS R01 AI117043
6 · The paper itself

Abstract

Carbapenem resistance is mainly mediated by carbapenemases or extended-spectrum β-lactamases (ESBL) plus a loss of porins. However, we have identified a

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsDrug Resistance, BacterialHumansKlebsiella InfectionsKlebsiella pneumoniaePorinsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsOmpK36 protein, Klebsiella pneumoniaePorinscarbapenem resistanceKlebsiellaOXA-663β-lactamases

Identifiers

PMID30126962
PMCPMC6201135
OpenAlexW2887183065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.