Evidence map›Paper›PMID 30126947›Full record

ArticleSexually transmitted infections2019

Detection of

Melinda B Nye, John Osiecki, Michael Lewinski, Oliver Liesenfeld, Stephen Young, Stephanie N Taylor, Rebecca A Lillis, Barbara A Body, Carol Eisenhut, Edward W Hook Iii and 1 more

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Sexually transmitted infections, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Identifying the Impact ofPathogens (Basel, Switzerland) · 2024
    Article
  3. Article
  4. A profile of the binx healthExpert review of molecular diagnostics · 2021
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Melinda B NyeLaboratory Corporation of America Holdings, Burlington, North Carolina, USA nyem@labcorp.com.
John OsieckiMedical and Scientific Affairs, Roche Molecular Systems, Pleasanton, California, USA.
Michael LewinskiMedical and Scientific Affairs, Roche Molecular Systems, Pleasanton, California, USA.
Oliver LiesenfeldMedical and Scientific Affairs, Roche Molecular Systems, Pleasanton, California, USA.
Stephen YoungTricore Reference Lab, Albuquerque, New Mexico, USA.
Stephanie N TaylorLouisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Rebecca A LillisLouisiana State University Health Sciences Center, New Orleans, Louisiana, USA.
Barbara A BodyLaboratory Corporation of America Holdings, Burlington, North Carolina, USA.
Carol EisenhutDCL Laboratories (now Laboratory Corporation of America), Indianapolis, Indiana, USA.
Edward W Hook IiiUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.
Barbara Van Der PolUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.
Materials Systems (United States) · USLabCorp (United States) · USLouisiana State University Health Sciences Center New Orleans · USUniversity of Alabama at Birmingham · USApplied Research Associates (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInfections due to

methodsSensitivity and specificity were estimated compared with a patient infected status determined using two US Food and Drug Administration-cleared nucleic acid amplification tests.

resultsAmong 6004 participants, 487 CT (8.1%) and 159 NG (2.6%) infections were identified. Sensitivity estimates for CT for women ranged from 91.2% to 97.6% depending on specimen type, and the estimate for male urine specimens was 98.4%. Specificity for CT ranged from 99.2% to 99.7%. Sensitivity estimates for NG ranged from 95.6% to 100.0% for women, and the estimate for men was 100.0%. Specificity for NG ranged from 99.3% to 100.0%.

conclusionsThe cobas CT/NG v2.0 test performs well using urogenital swabs, urine and cervical samples collected in PreservCyt solution.

Indexed as

Reagent Kits, DiagnosticAdultCervix UteriChlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHumansMaleMolecular Diagnostic TechniquesNeisseria gonorrhoeaeNucleic Acid Amplification TechniquesSensitivity and SpecificityVaginal SmearsYoung AdultReagent Kits, Diagnostic

Identifiers

PMID30126947
PMCPMC6580769
OpenAlexW2888381666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.