Evidence map›Paper›PMID 30126411›Full record

Trial reportBMC public health2018

Factors in the HIV risk environment associated with bacterial vaginosis among HIV-negative female sex workers who inject drugs in the Mexico-United States border region.

Jennifer P Jain, Claire C Bristow, Heather A Pines, Alicia Harvey-Vera, Gudelia Rangel, Hugo Staines, Thomas L Patterson, Steffanie A Strathdee

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00840658 (Epidemiologic Study on Changing HIV Risks Among FSW-IDUs on the Mexico-US Border), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00840658 phase2completednot on this map

Epidemiologic Study on Changing HIV Risks Among FSW-IDUs on the Mexico-US Border

TypeinterventionalSponsorSteffanie StrathdeeRan2008 to 2011Enrolled584ConditionsHIV, HIV InfectionsArmsInteractive injection and sexual risk intervention, Interactive Sexual Risk Intervention, Interactive Injection Risk Intervention, Lecture-format presentation
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Observational
  3. Hallmarks of Bacterial Vaginosis.Diagnostics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Evaluation of the Inhibitory Effects ofFrontiers in medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jennifer P JainDepartment of Medicine, University of California, San Diego, USA. j2jain@ucsd.edu.
Claire C BristowDepartment of Medicine, University of California, San Diego, USA.
Heather A PinesDepartment of Medicine, University of California, San Diego, USA.
Alicia Harvey-VeraDepartment of Medicine, University of California, San Diego, USA.
Gudelia RangelUS-Mexico Border Health Commission, Tijuana, Mexico.
Hugo StainesFacultad de Medicina, Universidad Autónoma de Ciudad Juarez, Ciudad Juárez, MX, Mexico.
Thomas L PattersonDepartment of Psychiatry, University of California, San Diego, USA.
Steffanie A StrathdeeDepartment of Medicine, University of California, San Diego, USA.
University of California, San Diego · USUniversidad Autónoma de Ciudad Juárez · MX

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Epidemiologic Study on Changing HIV Risks Among FSW-IDUs on the Mexico-US BorderR01DA023877 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2008 to 2012
$3.3M
National Institute on Drug Abuse (US) DA023877NIAID NIH HHS P30 AI036214NIDA NIH HHS R01 DA023877NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

backgroundBacterial vaginosis (BV) is the most common cause of vaginitis among women worldwide and is associated with increased susceptibility to sexually transmitted infections (STIs), including HIV. We aimed to determine the impact of the HIV risk environment on BV among female sex workers who inject drugs (FSW-PWIDs) in Tijuana and Ciudad Juarez, Mexico.

methodsWe performed a cross-sectional analysis utilizing baseline data from a randomized controlled trial evaluating a behavioral HIV prevention intervention. Participants underwent testing for BV using the OSOM BVBlue® Rapid Test (Genzyme Diagnostics, San Diego, CA) and completed a survey eliciting information on the HIV risk environment, sexual risk behaviors, and substance use. We applied logistic regression to identify correlates of BV in the physical, social, economic, and political HIV risk environments stratified by study site (Ciudad Juarez vs. Tijuana).

resultsIn total, 584 HIV-negative FSW-PWIDs (300 Ciudad Juarez; 284 Tijuana) were enrolled. The prevalence of BV was 39% (n = 228), which was higher in Ciudad Juarez (56.7%) compared to Tijuana (20.4%). In both cities, micro-level components of the physical HIV risk environment were associated with BV. In Ciudad Juarez, BV was associated with past experiences or threats of physical violence in response to proposed condom use (adjusted odds ratio [aOR] = 3.66, 95% confidence interval [CI]: 1.74-7.69, p = 0.001) and lifetime residence in Ciudad Juarez (aOR = 1.74, 95% CI: 1.05-2.87, p = 0.031). In Tijuana, BV was associated with the number of hours spent on the street daily in the past six months looking for, using, or dealing drugs, engaging in other income generating activities, or sleeping (aOR = 1.05, 95% CI: 1.001-1.097, p = 0.045).

conclusionsOur findings suggest that FSW-PWIDs' risk of BV may be shaped by the microphysical HIV risk environment. Addressing components of the physical risk environment, including interventions to reduce gender-based violence, may alleviate the burden of BV and subsequent susceptibility to HIV/STIs among FSW-PWIDs in the Mexico/US border region.

trial registrationNational Institute of Health (NIH) Clinical Trials Identifier NCT00840658 , and date of NIH trial registration February 7, 2009.

Indexed as

AdultCross-Sectional StudiesFemaleHIV InfectionsHumansMexicoPrevalenceRisk FactorsSex WorkersSubstance Abuse, IntravenousSurveys and QuestionnairesUnited StatesVaginosis, BacterialBacterial vaginosis (BV)Female sex workers who inject drugs (FSW-PWIDs)HIV risk environment and gender-based violenceMexico

Identifiers

PMID30126411
PMCPMC6102857
OpenAlexW2886798693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.