Evidence map›Paper›PMID 30126406›Full record

ArticleBMC public health2018

Parental socioeconomic position and midlife allostatic load: a study of potential mediators.

Dinne S Christensen, Trine Flensborg-Madsen, Ellen Garde, Åse M Hansen, Jolene M Pedersen, Erik L Mortensen

Abstract read
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In one paragraph

Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Stress, Well-Being, and Reproduction in Wildlife.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dinne S ChristensenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Øster Farimagsgade 5A, 1353, Copenhagen K, Denmark. dinnesc@sund.ku.dk.ORCID http://orcid.org/0000-0002-3568-3556
Trine Flensborg-MadsenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Øster Farimagsgade 5A, 1353, Copenhagen K, Denmark.
Ellen GardeSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Øster Farimagsgade 5A, 1353, Copenhagen K, Denmark.
Åse M HansenSection of Social Medicine, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen K, Denmark.
Jolene M PedersenCenter for Healthy Aging, University of Copenhagen, 3B, Blegdamsvej, Copenhagen N,, Denmark.
Erik L MortensenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Øster Farimagsgade 5A, 1353, Copenhagen K, Denmark.

Funding

LONG-TERM CONSEQUENCES OF PRENATAL EXPOSURE TO HORMONESR01HD017655 · NICHD · INDIANA UNIVERSITY BLOOMINGTON · PI REINISCH, JUNE M · 1985 to 1985
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Danish National Board of Health 1400/2-4-1997Danish Research Council 9700093National Institute of Child Health and Human Development HD-17655 and HD-20263National Institute of Drug Abuse DA05056Velux Fonden 26145 and 31539
6 · The paper itself

Abstract

backgroundThe mechanisms underlying the association of parental socioeconomic position with later life allostatic load remain unclear. The present study aims to examine potential pathways underlying this association: personality, social relations, intelligence and education.

methodsThe study comprised 361 members of the Copenhagen Perinatal Cohort who participated in two subsequent follow-ups: the Prenatal Development Project (mean age 27 years) and the Copenhagen Aging and Midlife Biobank study (mean age 50 years). Allostatic load was based on 14 biomarkers representing the inflammatory, metabolic and cardiovascular system measured at midlife. Information on potential mediators was collected in young adulthood, and their role in the association of parental socioeconomic position with midlife allostatic load were examined in linear regression path analyses.

resultsParental socioeconomic position at one year was inversely associated with midlife allostatic load (β = - 0.238, p < .001). No mediation effects were found for personality or social relations. In a model including intelligence and education, a significant indirect effect was found for education (β = - 0.151, p < .001). A significant direct effect remained (β = - 0.111, p = .040).

conclusionsParental socioeconomic position was inversely associated with allostatic load in midlife. Results suggest that part of this association was mediated by education. A better understanding of the non-cognitive pathways related to education is an important prerequisite for the development of effective intervention strategies.

Indexed as

AllostasisParentsSocial ClassCohort StudiesEducational StatusFemaleHumansIntelligenceInterpersonal RelationsLinear ModelsMaleMiddle AgedPersonalityAllostatic loadEducationIntelligenceParental socioeconomic positionPersonalitySocial relations

Identifiers

PMID30126406
PMCPMC6102839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.