Evidence map›Paper›PMID 30126382›Full record

Observational studyBMC public health2018

Effectiveness and safety of electronic cigarettes among sole and dual user vapers in Kuantan and Pekan, Malaysia: a six-month observational study.

Mohamad Haniki Nik Mohamed, Azizur Rahman, Shazia Jamshed, Syed Mahmood

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Perception of E-cigarette Use among Adult Users in China: A Mixed-method Study.International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohamad Haniki Nik MohamedDepartment of Pharmacy Practice, Kulliyyah of Pharmacy, International Islamic University of Malaysia (IIUM), Jalan Sultan Ahmed shah, 25200, Kuantan campus, Pahang, Malaysia.
Azizur RahmanDepartment of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, UCSI University, 26000, Cheras, Kuala Lumpur, Malaysia. aziz@ucsiuniversity.edu.my.
Shazia JamshedDepartment of Pharmacy Practice, Kulliyyah of Pharmacy, International Islamic University of Malaysia (IIUM), Jalan Sultan Ahmed shah, 25200, Kuantan campus, Pahang, Malaysia.
Syed MahmoodDepartment of Pharmaceutical Engineering, Faculty of Engineering Technology, University Malaysia Pahang, 26300, Gambang, Pahang, Malaysia.
International Islamic University Malaysia · MYUCSI University · MYUniversiti Malaysia Pahang Al-Sultan Abdullah · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent studies on electronic cigarettes (ECs) have assessed the smoking cessation effectiveness and safety of EC among sole EC users. However, in Malaysia and elsewhere, most EC users also smoke conventional cigarettes (CCs). We aimed to investigate nicotine cessation for both ECs and CCs. Additionally, safety issues among sole EC and dual (EC and CC) users over a six-month period were reported.

methodsWe observed 218 sole Malaysian EC and dual users over 6 months from June 2015 to November 2015. Both groups underwent exhaled breath carbon monoxide and saliva cotinine analyses to verify their nicotine cessation from both EC and CC use. Adverse events and withdrawal symptoms were assessed based on self-reports.

resultsOnly 3.3% of observed users quit both ECs and CCs, whereas 20.5% quit smoking CCs. Quitting ECs and CCs was significantly higher among sole EC users (5 vs 2, respectively; OR: 5.62; P = 0.036) than it was among dual users, a result that was similar for CCs smoking (29 vs. 15; OR: 6.33; P ≤ 0.001). No severe health issues were reported over the entire study period.

conclusionThe rates of quitting CCs and ECs were higher in sole EC users than those in dual users. No serious health effects were reported over 6 months in either group. ECs may serve as a smoking cessation aid in Malaysia, but appropriate regulations are necessary to encourage sole EC use to ensure product quality. Large randomised clinical trials (RCTs) with a longer follow-up are required to better measure the effectiveness and safety of ECs use alone and in combination with CCs.

Indexed as

Electronic Nicotine Delivery SystemsAdultFemaleFollow-Up StudiesHumansMalaysiaMaleSmokersSmokingSmoking CessationTobacco ProductsYoung AdultCarbon monoxideConventional cigaretteEffectivenessElectronic cigaretteSafety

Identifiers

PMID30126382
PMCPMC6102911
OpenAlexW2888449405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.