ArticleBMC plant biology2018
Identification and characterization of histone modification gene family reveal their critical responses to flower induction in apple.
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Identification and Characterization of Histone Modification Gene Families and Their Expression Patterns During Pod and Seed Development in Peanut.International journal of molecular sciences · 2025Article
- Genome-Wide Analysis of the Histone Modification Gene (Plants (Basel, Switzerland) · 2024Article
- Genome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars.BMC genomics · 2024Article
- Cloning and Functional Analysis of thePlants (Basel, Switzerland) · 2023Article
- Long distance signalling and epigenetic changes in crop grafting.Frontiers in plant science · 2023Review
- From Floral Induction to Blooming: The Molecular Mysteries of Flowering in Woody Plants.International journal of molecular sciences · 2022Review
- Genome-Wide Identification and Spatial Expression Analysis of Histone Modification Gene Families in the Rubber DandelionPlants (Basel, Switzerland) · 2022Article
- Comprehensive molecular evaluation of the histone methyltransferase gene family and their important roles in two-line hybrid wheat.BMC plant biology · 2022Article
- Identification and expression analysis of histone modification gene (HM) family during somatic embryogenesis of oil palm.BMC genomics · 2022Article
- Bioinformatics and expression analysis of histone modification genes in grapevine predict their involvement in seed development, powdery mildew resistance, and hormonal signaling.BMC plant biology · 2020Article
- Epigenetic Changes and Transcriptional Reprogramming Upon Woody Plant Grafting for Crop Sustainability in a Changing Environment.Frontiers in plant science · 2020Review
- Identification, Evolution, and Expression Profiling of Histone Lysine Methylation Moderators inPlants (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHistone methylation and acetylation regulate biological processes in plants through various histone modifications (HMs) gene families. However, knowledge of HMs genes is limited in horticultural deciduous trees, including apple (Malus domestica).
resultsHere, a comprehensive study of identifying and investigating HMs genes was performed using the recently published apple genome. In total, 198 MdHMs were identified, including 71 histone methyltransferases, 44 histone demethylases, 57 histone acetylases, and 26 histone deacetylases. Detailed analysis of the MdHMs, including chromosomes locations, gene structures, protein motif and protein-protein interactions were performed, and their orthologous genes were also predicted against nine plant species. Meanwhile, a syntenic analysis revealed that tandem, segmental, and whole genome duplications were involved in the evolution and expansion of the MdHMs gene family. Most MdHMs underwent purifying selection. The expression profiles of 198 MdHMs were investigated in response to 6-BA treatment and different flowering varieties (easy-flowering 'Yanfu No.6' and difficult-flowering 'Nagafu No.2') using transcriptome sequencing data, and most MdHMs were involved in flower induction processes. Subsequent quantitative real-time PCR was then performed to confirm the expression levels of candidate MdHMs under different flowering-related circumstances.
conclusionMdHMs were involved in, and responsive to, flower induction in apple. This study established an MdHMs platform that provided valuable information and presented enriched biological theories on flower induction in apple. The data could also be used to study the evolutionary history and functional prospects of MdHMs genes, as well as other trees.
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