Evidence map›Paper›PMID 30126355›Full record

Observational studyBMC infectious diseases2018

Incident HIV infection has fallen rapidly in men who have sex with men in Melbourne, Australia (2013-2017) but not in the newly-arrived Asian-born.

Nicholas A Medland, Eric P F Chow, Timothy H R Read, Jason J Ong, Marcus Chen, Ian Denham, Praveena Gunaratnum, Christopher K Fairley

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Nicholas A MedlandMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia. nmedland@mshc.org.au.ORCID http://orcid.org/0000-0003-0403-8930
Eric P F ChowMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Timothy H R ReadMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Jason J OngMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Marcus ChenMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Ian DenhamMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Praveena GunaratnumThe Kirby Institute for Infection and Immunity, University of New South Wales, Sydney, Australia.
Christopher K FairleyMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.
Melbourne Sexual Health Centre · AUUniversity of London · GBUNSW Sydney · AU

Funding

National Health and Medical Research Council 1091226National Health and Medical Research Council 1091536National Health and Medical Research Council 1094518National Health and Medical Research Council 1104781
6 · The paper itself

Abstract

backgroundWe examined differences in incident HIV infection between newly-arrived Asian-born and other men who have sex with men (MSM) after the introduction of universal HIV treatment guidelines in 2015 and pre-exposure prophylaxis in 2016.

methodsClinical, demographic, laboratory and behavioural data on MSM presenting for HIV testing at the Melbourne Sexual Health Centre from July 2013 to June 2017 were extracted. We compared the proportion of newly-arrived (four years or less in Australia), Asian-born and other MSM tested each year who were diagnosed with incident HIV infection (negative test within one year or diagnosis with indeterminate or negative Western Blot).

resultsWe analysed 35,743 testing episodes in 12,180 MSM, including 2781 testing episodes in 1047 newly-arrived Asian-born MSM. The proportion of other MSM tested each year who were diagnosed with incident HIV infection fell from 0.83% in 2014 to 0.38% in 2017 (p = .001), but did not fall in newly-arrived Asian-born MSM (from 1.18% in 2014 to 1.56% in 2017, p = .76). In the multivariate logistic regression, in 2016/2017 but not in 2014/2015, being newly-arrived Asian-born was associated with an increased odds of diagnosis of incident HIV infection (aOR 3.29, 95%CI 1.82-5.94, p < .001).

conclusionsThe epidemiology of HIV in Melbourne Australia has changed dramatically. While there has been an overall reduction amongst MSM, the incidence of HIV in newly-arrived Asian-born MSM remains high. Failing to address these new inequalities leaves individuals at risk and may offset the population benefit of biomedical HIV prevention.

Indexed as

AdultAsian PeopleAustraliaEmigrants and ImmigrantsFemaleHIVHIV InfectionsHomosexuality, MaleHumansIncidenceMalePre-Exposure ProphylaxisPregnancyRetrospective StudiesSexual and Gender MinoritiesWhite PeopleHIVIncidencePre-exposure prophylaxisSexual transmissionTreatment as prevention

Identifiers

PMID30126355
PMCPMC6102820
OpenAlexW2888384064

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.