Evidence map›Paper›PMID 30126351›Full record

ArticleBMC pregnancy and childbirth2018

Pre-pregnancy cardiovascular risk factors and racial disparities in birth outcomes: the Bogalusa Heart Study.

Emily W Harville, Leann Myers, Tian Shu, Maeve E Wallace, Lydia A Bazzano

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emily W HarvilleDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, 1440 Canal St. Ste. 2001, #8318, New Orleans, LA, 70112-2715, USA. eharvill@tulane.edu.ORCID http://orcid.org/0000-0003-0319-0922
Leann MyersDepartment of Global Biostatistics and Data Science, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Tian ShuDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, 1440 Canal St. Ste. 2001, #8318, New Orleans, LA, 70112-2715, USA.
Maeve E WallaceDepartment of Global Community Health and Behavioral Sciences, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Lydia A BazzanoDepartment of Epidemiology, Tulane School of Public Health and Tropical Medicine, 1440 Canal St. Ste. 2001, #8318, New Orleans, LA, 70112-2715, USA.
Tulane University · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Lifespan Cardiovascular Risk Exposures and Alzheimer-related brain health: Bogalusa Heart StudyRF1AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA, CARMICHAEL, OWEN T. · 2019 to 2022
$4.2M
The Role of Vascular Aging in Cognitive and Physical Function - Diversity SupplementR01AG041200 · NIA · TULANE UNIVERSITY OF LOUISIANA · PI BAZZANO, LYDIA · 2012 to 2017
$2.9M
Long-Term Burden of Maternal Cardiovascular Risk Factors and Birth OutcomesR01HD069587 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI HARVILLE, EMILY WHEELER · 2012 to 2015
$2.1M
CHILDHOOD PREDICTOR OF ADULT CORONARY ARTERY DISEASER01HD032194 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI BERENSON, GERALD S · 1994 to 1998
–
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD032194Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD069587National Heart, Lung, and Blood Institute P50HL015103National Heart, Lung, and Blood Institute R01HL016592National Institute on Aging R01AG041200NHLBI NIH HHS P50 HL015103NIA NIH HHS R01 AG041200NIA NIH HHS RF1 AG041200NICHD NIH HHS R01 HD032194NICHD NIH HHS R01 HD069587NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

backgroundRacial disparities in birth outcomes are mirrored in cardiovascular health. Recently there have been calls for more attention to preconception and interconceptional health in order to improve birth outcomes, including as a strategy to reduce black-white disparities.

methodsAs part of a larger study of cardiovascular and reproductive health ("Bogalusa Babies"), female participants were linked to their children's birth certificates for Louisiana, Mississippi, and Texas births from 1982 to 2009. Three thousand and ninety-five women were linked to birth certificate data. Birth outcomes were defined as low birthweight (LBW) birthweight < 2500 g; preterm birth (PTB), > 3 weeks early; small for gestational age (SGA), <10th percentile for gestational age (percentiles based on study population); large for gestational age (LGA) >90th percentile for gestational age]. Cardiovascular measures (blood pressure, lipids, glucose, insulin) at the visit closest in time but prior to the pregnancy was examined as predictors of birth outcomes using logistic models adjusted for covariates.

resultsOnly a few cardiovascular risk factors were associated with birth outcomes. Triglycerides were associated with higher risk of LBW among whites (aOR 1.05, 95% 1.01-1.10). Higher glucose was associated with a reduction in risk of SGA for black women (aOR 0.85, 95% CI 0.76-0.95), but not whites (p for interaction = 0.02). Clear racial disparities were found, but they were reduced modestly (LBW/SGA) or not at all (PTB/LGA) after CVD risk factors were adjusted for.

conclusionsThis analysis does not provide evidence for preconception cardiovascular risk being a strong contributor to racial disparities.

Indexed as

Health Status DisparitiesAdolescentAdultBirth WeightBlood GlucoseBlood PressureCardiovascular DiseasesChildChild, PreschoolFemaleGestational AgeHumansInfant, NewbornLipidsPregnancyPregnancy ComplicationsBlood GlucoseLipidsBirth weight, lowCholesterolContinental population groupsGlucoseInfant, small for gestational agePremature birth

Identifiers

PMID30126351
PMCPMC6102890
OpenAlexW2888309746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.