Evidence map›Paper›PMID 30126294›Full record

ArticleAIDS care2019

Role of pre-stroke immunity in ischemic stroke mechanism among patients with HIV.

Jose Gutierrez, Camilla Ingrid Hatleberg, Henry Evans, Michael T Yin

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Echocardiography in HIV Disease.Current cardiology reports · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Cerebrovascular Contributions to Neurocognitive Disorders in People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2021
    Article
  7. Review
  8. Article
  9. Stroke in HIV.The Canadian journal of cardiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jose Gutierreza Department of Neurology , New York Presbyterian Hospital/ Columbia University Medical Center , New York , NY , USA.ORCID 0000-0002-2175-8078
Camilla Ingrid Hatlebergb CHIP, Dept. of Infectious Diseases Section 2100, Finsencentret, Rigshospitalet , University of Copenhagen , Copenhagen , Denmark.
Henry Evansc College of Physician and Surgeons , Columbia University Medical Center , New York , NY , USA.
Michael T Yind Department of Medicine, Division of Infectious Diseases , New York Presbyterian Hospital/Columbia University Medical Center , New York , NY , USA.
NewYork–Presbyterian Hospital · USColumbia University Irving Medical Center · USUniversity of Copenhagen · DK

Funding

Columbia Partnership for Prevention and Control of HIV/AIDS Clinical Trials UnitUM1AI069470 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK · 2012 to 2026
$44.8M
Multidisciplinary HIV Training ProgramT32AI007387 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Daniel R. Kuritzkes · 1990 to 2026
$8.8M
NIAID NIH HHS T32 AI007387NIAID NIH HHS UM1 AI069470
6 · The paper itself

Abstract

Individuals with HIV are at a higher risk of stroke compared to uninfected populations. The role of HIV-related immunosuppression in stroke mechanism is uncertain. Our aim is to test the hypothesis that stroke mechanisms among HIV+ individuals vary according to preceding CD4 counts. We carried out a retrospective chart review of inpatient admissions for ICD-9 defined ischemic events (TIA or stroke) in HIV+ individuals from 2002 to 2016 at a tertiary care center. Stroke mechanisms were ascertained based on radiographic and clinical presentation, and adjudicated by the treating team and confirmed separately by a vascular neurologist. Vascular risk factors, use of antiretroviral drugs (ARVs), nadir CD4 and current CD4 counts (cells/mm

Indexed as

AdultAgedAnti-Retroviral AgentsAtherosclerosisCD4 Lymphocyte CountFemaleHIV InfectionsHumansIschemic Attack, TransientMaleMiddle AgedRetrospective StudiesRisk FactorsStrokeAnti-Retroviral AgentsatherosclerosisHIVsmall artery diseasestrokestroke mechanism

Identifiers

PMID30126294
PMCPMC6289722
OpenAlexW2888124435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.