Evidence map›Paper›PMID 30126245›Full record

ArticleMolecules (Basel, Switzerland)2018

Antimicrobial Photodynamic Therapy Mediated by Curcumin-Loaded Polymeric Nanoparticles in a Murine Model of Oral Candidiasis.

Vinicius Tatsuyuji Sakima, Paula Aboud Barbugli, Paulo Sérgio Cerri, Marlus Chorilli, Juliana Cabrini Carmello, Ana Cláudia Pavarina, Ewerton Garcia de Oliveira Mima

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy onInternational journal of molecular sciences · 2024
    Pooled it
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  16. A Denture Use Model Associated withJournal of fungi (Basel, Switzerland) · 2022
    Article
  17. Effect of curcumin-encapsulated PluronicLasers in medical science · 2022
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vinicius Tatsuyuji SakimaSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. sakima888@gmail.com.
Paula Aboud BarbugliSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. pabfarma@yahoo.com.br.
Paulo Sérgio CerriSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. pcerri@foar.unesp.br.ORCID 0000-0001-5756-5828
Marlus ChorilliSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, São Paulo, Brazil. chorilli@fcfar.unesp.br.ORCID 0000-0002-6698-0545
Juliana Cabrini CarmelloSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. cabrini.juliana@gmail.com.
Ana Cláudia PavarinaSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. pavarina@foar.unesp.br.
Ewerton Garcia de Oliveira MimaSchool of Dentistry, São Paulo State University (UNESP), Araraquara 14801-903, São Paulo, Brazil. ewertonmima@foar.unesp.br.ORCID 0000-0002-9575-7625
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial photodynamic therapy (aPDT) has been proposed as an alternative method for oral candidiasis (OC), while nanocarriers have been used to improve the water solubility of curcumin (CUR). The aim of this study is to encapsulate CUR in polymeric nanoparticles (NPs) and to evaluate its photodynamic effects on a murine model of OC. Anionic and cationic CUR-NP is synthesized using poly-lactic acid and dextran sulfate and then characterized. Female mice are immunosuppressed and inoculated with

Indexed as

NanoparticlesPhotochemotherapyPolymersAnimalsAntifungal AgentsBiomarkersCandida albicansCandidiasis, OralCurcuminDisease Models, AnimalDrug CarriersDrug CompoundingDrug LiberationDrug StabilityFemaleImmunohistochemistryAntifungal AgentsBiomarkersCurcuminDrug CarriersPolymersCandida albicanscurcuminkeratinsmicenanoparticlesoral candidiasisphotochemotherapy

Identifiers

PMID30126245
PMCPMC6222858
OpenAlexW2886209938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.