ArticleInternational journal of environmental research and public health2018
Short-Term Effects of Heat on Mortality and Effect Modification by Air Pollution in 25 Italian Cities.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Modification of heat-related effects on mortality by air pollution concentration, at small-area level, in the Attica prefecture, Greece.Environmental health : a global access science source · 2024Pooled it
- Joint effect of heat and air pollution on mortality in 620 cities of 36 countries.Environment international · 2023Pooled it
- Global Health Impacts for Economic Models of Climate Change: A Systematic Review and Meta-Analysis.Annals of the American Thoracic Society · 2022Pooled it
- Synergistic health effects of air pollution, temperature, and pollen exposure: a systematic review of epidemiological evidence.Environmental health : a global access science source · 2020Pooled it
- Article
- Associations of PMBMC public health · 2026Article
- Mortality risk associated with heatwave exposure based on daily maximum, minimum, and combined temperature thresholds.European journal of public health · 2026Article
- Independent and interactive effects of wet bulb globe temperature and air pollution exposures on suicide mortality.Environment international · 2026Article
- Development and two-city validation of a Temperature-Sensitive Air Quality Health Index incorporating synergistic effects of air pollution and thermal stress.Frontiers in public health · 2026Article
- Mortality Related to Climate Change and Environmental Hazards in the Mediterranean Region: A Scoping Review.Current environmental health reports · 2025Article
- Mortality Risk from Chronic Ischemic Heart Disease Associated with Short-Term Co-Exposure to Summer Heatwave and Ozone.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Random Forest and Feature Importance Measures for Discriminating the Most Influential Environmental Factors in Predicting Cardiovascular and Respiratory Diseases.International journal of environmental research and public health · 2024Article
- Emerging concern on air pollution and health: Trade-off between air pollution exposure and physical activity.Eco-Environment & Health · 2024Article
- The effect modification of PMEnvironmental health and preventive medicine · 2024Article
- External exposome and all-cause mortality in European cohorts: the EXPANSE project.Frontiers in epidemiology · 2024Article
- Analyzing the Interactions between Environmental Parameters and Cardiovascular Diseases Using Random Forest and SHAP Algorithms.Reviews in cardiovascular medicine · 2023Article
- Peculiar weather patterns effects on air pollution and COVID-19 spread in Tokyo metropolis.Environmental research · 2023Observational
- Climatic influences on cardiovascular diseases.World journal of cardiology · 2022Review
- Article
- The association between gaseous pollutants and non-accidental mortality: a time series study.Environmental geochemistry and health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence on the health effects of extreme temperatures and air pollution is copious. However few studies focused on their interaction. The aim of this study is to evaluate daily PM10 and ozone as potential effect modifiers of the relationship between temperature and natural mortality in 25 Italian cities. Time-series analysis was run for each city. To evaluate interaction, a tensor product between mean air temperature (lag 0⁻3) and either PM10 or ozone (both lag 0⁻5) was defined and temperature estimates were extrapolated at low, medium, and high levels of pollutants. Heat effects were estimated as percent change in mortality for increases in temperature between 75th and 99th percentiles. Results were pooled by geographical area. Differential temperature-mortality risks by air pollutants were found. For PM10, estimates ranged from 3.9% (low PM10) to 14.1% (high PM10) in the North, from 3.6% to 24.4% in the Center, and from 7.5% to 21.6% in the South. Temperature-related mortality was similarly modified by ozone in northern and central Italy, while no effect modification was observed in the South. This study underlines the synergistic effects of heat and air pollution on mortality. Considering the predicted increase in heat waves and stagnation events in the Mediterranean countries such as Italy, it is time to enclose air pollution within public health heat prevention plans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.