Evidence map›Paper›PMID 30125443›Full record

ArticleAngewandte Chemie (International ed. in English)2018

Synthesis of N-H Bearing Imidazolidinones and Dihydroimidazolones Using Aza-Heck Cyclizations.

Feiyang Xu, Scott A Shuler, Donald A Watson

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Cyclopropane-FusedJournal of the American Chemical Society · 2022
    Article
  4. Article
  5. Electrophilic Aminating Agents in Total Synthesis.Angewandte Chemie (International ed. in English) · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Synthesis of Indolines and Derivatives by Aza-Heck Cyclization.Angewandte Chemie (International ed. in English) · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Feiyang XuDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
Scott A ShulerDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.
Donald A WatsonDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716, USA.ORCID 0000-0003-4864-297X

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI SCHMITZ, KARL ROBERT · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
Q-Exactive Orbitrap LC-MC/MS SystemS10OD016267 · OD · UNIVERSITY OF DELAWARE · PI JOHNSTON, MURRAY V · 2013 to 2013
$573k
High Performance Digital NMR SpectrometerS10RR026962 · NCRR · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026962NIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM110758NIH HHS P20 GM104316, P30 GM110758, S10 RR02692NIH HHS S10 OD016267
6 · The paper itself

Abstract

The synthesis of unsaturated, unprotected imidazolidinones via an aza-Heck reaction is described. This palladium-catalyzed process allows for the cyclization of N-phenoxy ureas onto pendant alkenes. The reaction has broad functional group tolerance, can be applied to complex ring topologies, and can be used to directly prepare mono- and bis-unprotected imidazolidinones. By addition of Bu

Indexed as

CatalysisCyclizationFactor Xa InhibitorsHumansHydrogenImidazolesImidazolidinesNitrogenPalladiumFactor Xa InhibitorsHydrogenImidazolesImidazolidinesimidazoloneNitrogenPalladiumaza-Heck reactioncatalysisdihydroimidazolonesimidazolidinonespalladium

Identifiers

PMID30125443
PMCPMC6141047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.