Evidence map›Paper›PMID 30125383›Full record

ArticleMagnetic resonance in medicine2019

Influences of experimental parameters on chemical exchange saturation transfer (CEST) metrics of brain tumors using animal models at 4.7T.

Hye-Young Heo, Yi Zhang, Shanshan Jiang, Jinyuan Zhou

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Study of Power Equivalent Continuous Approximation Based on the Recent Consensus Recommendations for Brain Tumor Imaging with Pulsed Chemical Exchange Saturation Transfer at 3T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hye-Young HeoDivison of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland.ORCID 0000-0002-7297-2015
Yi ZhangDivison of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland.ORCID 0000-0001-8738-1851
Shanshan JiangDivison of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland.
Jinyuan ZhouDivison of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland.

Funding

Amide Proton Transfer (APT) MRI of Brain Tumors at 3T and 7TR01EB009731 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2009 to 2016
$2.9M
Academic-Industrial Partnership to Develop Clinical Brain Cancer ImagingR01CA166171 · NCI · JOHNS HOPKINS UNIVERSITY · PI VAN ZIJL, PETER CM, ZHOU, JINYUAN · 2013 to 2017
$2.4M
Amide Proton Transfer (APT) MRI of Brain Tumors at 3TR01CA228188 · NCI · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2019 to 2022
$1.6M
Highly Accelerated Chemical Exchange Saturation Transfer MRI Using Compressed SensingR21CA227783 · NCI · JOHNS HOPKINS UNIVERSITY · PI HEO, HYE YOUNG · 2018 to 2019
$385k
NCI NIH HHS R01 CA166171NCI NIH HHS R01 CA228188NCI NIH HHS R21 CA227783NIBIB NIH HHS R01 EB009731NIH HHS R01CA166171NIH HHS R01CA228188NIH HHS R01EB009731NIH HHS R21CA227783
6 · The paper itself

Abstract

purposeTo investigate the dependence of magnetization transfer ratio asymmetry at 3.5 ppm (MTR

methodsModified Bloch equation-based simulations using 2-pool and 5-pool exchange models and in vivo rat brain tumor experiments at 4.7T were performed with varied RF saturation power levels, saturation lengths, and relaxation delays. The MTR

resultsThe MTR

conclusionTumor MTR

Indexed as

AlgorithmsAnimalsBrainBrain NeoplasmsComputer SimulationContrast MediaDisease Models, AnimalGliomaImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMagnetic Resonance ImagingMonte Carlo MethodNeoplasm TransplantationProtonsRatsContrast MediaProtonsWaterAPTbrain tumorCESTRF saturation lengthRF saturation power

Identifiers

PMID30125383
PMCPMC6258283

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.