Evidence map›Paper›PMID 30125047›Full record

Observational studyClinical cardiology2018

Design and rationale of the atrial fibrillation occurring transiently with stress (AFOTS) follow-up cohort study.

William F McIntyre, Pablo A Mendoza, Emilie P Belley-Côté, Richard P Whitlock, Kevin J Um, Natalie Maystrenko, P J Devereaux, David Conen, Jorge A Wong, Stuart J Connolly and 1 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. COVID-19 and AF: What About the Long Game?JACC. Clinical electrophysiology · 2021
    Article
  2. Review
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

William F McIntyreDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.ORCID http://orcid.org/0000-0001-6082-7542
Pablo A MendozaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Emilie P Belley-CôtéDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Richard P WhitlockDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Kevin J UmPopulation Health Research Institute, Hamilton, Ontario, Canada.
Natalie MaystrenkoPopulation Health Research Institute, Hamilton, Ontario, Canada.
P J DevereauxDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
David ConenDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Jorge A WongDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Stuart J ConnollyDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Jeff S HealeyDivision of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
Population Health Research Institute · CA

Funding

Canadian Institutes of Health ResearchCanadian Stroke Prevention Intervention Network (C-SPIN)C-SPINHeart and Stroke FoundationHeart and Stroke Foundation of Canada G-18-0022204McMaster University, Cooper FoundationThe Canadian Cardiovascular Society AF Awards programThe Canadian Cardiovascular Society-Bayer Vascular Awards program
6 · The paper itself

Abstract

Atrial fibrillation occurring transiently with stress (AFOTS) describes the first detection of AF in a patient who is hospitalized for a non-cardiac medical illness or following non-cardiac surgery. Uncertainty exists whether episodes of AFOTS are due to reversible precipitants and will not recur after recovery, or if they are paroxysmal atrial fibrillation (AF) that is detected during inpatient cardiac monitoring. Previous studies have used retrospective, non-systematic and ultimately low-sensitivity protocols to investigate the recurrence of AF in patients with AFOTS. The prospective, multi-center, investigator-initiated AFOTS Follow-Up Cohort Study will enroll 138 case patients with AFOTS in the setting of non-cardiac surgery or medical illness, matched 1:1 with control patients for age, sex, stressor, and hospital unit. Participants will wear a 14-day ECG heart monitor at 1 and 6 months after hospital discharge. Over 12 months of follow-up, we will collect data regarding participant's medications, and clinical events. The primary endpoint is detection of 30 or more seconds of AF after hospital discharge. To date, 50% of the target sample has been enrolled. The study is expected to complete enrolment in mid-2019 and conclude 1 year later. The AFOTS follow-up study will employ a systematic protocol to detect AF and will provide a precise and valid estimate of AF recurrence following AFOTS. This study will establish whether patients with AFOTS have an increased propensity to AF after hospitalization as compared to matched controls and may inform the management of this population.

Indexed as

Propensity ScoreStress, PhysiologicalAgedAged, 80 and overAtrial FibrillationCohort StudiesElectrocardiography, AmbulatoryFemaleFollow-Up StudiesHumansIncidenceMaleOntarioPatient DischargeProspective StudiesRecurrenceatrial fibrillationelectrocardiography ambulatory ECGstroke prevention

Identifiers

PMID30125047
PMCPMC6489868
OpenAlexW2888500718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.