ArticleAmerican journal of epidemiology2018
Association Between 20-Year Trajectories of Nonoccupational Physical Activity From Midlife to Old Age and Biomarkers of Cardiovascular Disease: A 20-Year Longitudinal Study of British Men.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Trajectories of healthy lifestyles score and cardiovascular disease: a cohort study.Family medicine and community health · 2026Article
- Associations of Mid- and Late-Life Fasting Blood Glucose Levels With Dementia Risk Among Patients With Diabetes: Framingham Heart Study.European journal of neurology · 2025Article
- Article
- Social interaction trajectories and all-cause mortality in older adults: the Otassha study.Frontiers in public health · 2023Article
- Associations of physical activity participation trajectories with subsequent motor function declines and incident frailty: A population-based cohort study.Frontiers in psychiatry · 2022Article
- Life-Course Trajectories of Physical Activity and Melanoma Risk in a Large Cohort of Norwegian Women.Clinical epidemiology · 2022Article
- Nutrition in the Actual COVID-19 Pandemic. A Narrative Review.Nutrients · 2021Review
- Influence of Baseline Physical Activity as a Modifying Factor on COVID-19 Mortality: A Single-Center, Retrospective Study.Infectious diseases and therapy · 2021Article
- Physical Activity, Sport Practice and Cardiovascular Risk Factors in Workers From a Public Hospital: A Trajectory Analysis.Frontiers in cardiovascular medicine · 2021Article
- Investigation of the associations between physical activity, self-regulation and educational outcomes in childhood.PloS one · 2021Article
- Long-term incidence of cardiovascular outcomes in the middle-aged and elderly with different patterns of physical activity: Tehran lipid and glucose study.BMC public health · 2020Article
- Physical Activity Trajectories among Persons of Turkish Descent Living in Germany-A Cohort Study.International journal of environmental research and public health · 2020Article
- Trajectories of physical activity from midlife to old age and associations with subsequent cardiovascular disease and all-cause mortality.Journal of epidemiology and community health · 2020Article
- Use of an Exposome Approach to Understand the Effects of Exposures From the Natural, Built, and Social Environments on Cardio-Vascular Disease Onset, Progression, and Outcomes.Frontiers in public health · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The trajectories of physical activity (PA) from midlife into old age and their associations with established and novel cardiovascular disease (CVD) risk factors in later life remain unclear. This study examined associations between 20-year nonoccupational PA trajectories and a range of CVD biomarkers at ages 60-79 years. We used data from a sample of 3,331 men (mean baseline age = 50.2 ± 5.8 years) recruited in 1978-1980, with follow-up after 12, 16, and 20 years, reporting habitual nonoccupational PA at each wave. At the 20-year follow-up, surviving men attended a physical examination and provided a fasting blood sample. Group-based trajectory modeling was used to identify trajectories. Adjusted regression analyses examined the association between trajectory-group membership and several cardiometabolic, cardiac, and inflammatory markers at follow-up. Three distinct 20-year trajectories were identified: low/decreasing (21.3%), light/stable (51.8%), and moderate/increasing (27.0%). Compared with the low/decreasing group, membership in the light/stable and moderate/increasing trajectory groups was associated with a more favorable cardiometabolic profile and lower levels of inflammation and endothelial dysfunction. Although following a moderate-increasing PA trajectory was most favorable, more modest but sustained doses of PA into old age may be sufficient to lower CVD risk.
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