Evidence map›Paper›PMID 30124404›Full record

ArticleEmerging infectious diseases2018

Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice.

Chaitanya Kurhade, Sarah Schreier, Yi-Ping Lee, Loreen Zegenhagen, Marika Hjertqvist, Gerhard Dobler, Andrea Kröger, Anna K Överby

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Flaviviruses-Induced Neurological Sequelae.Pathogens (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chaitanya Kurhade
Sarah Schreier
Yi-Ping Lee
Loreen Zegenhagen
Marika Hjertqvist
Gerhard Dobler
Andrea Kröger
Anna K Överby

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

Indexed as

AnimalsDisease Models, AnimalEncephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneFemaleHumansMiceMice, Inbred C57BLSeverity of Illness IndexSpecies SpecificityVirulencearboviral diseasesflavivirusGermanypathogenesisSwedentick-borne encephalitisTick-borne encephalitis virusticksvector-borne infectionsviruses

Identifiers

PMID30124404
PMCPMC6106420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.