ArticleEmerging infectious diseases2018
Distinguishing Japanese Spotted Fever and Scrub Typhus, Central Japan, 2004- 2015.
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 48 citations in OpenAlex.
- Tsutsugamushi Disease in a Non-endemic Season and Region: Suspected Indoor Exposure via Pet-associated Vector Entry.Internal medicine (Tokyo, Japan) · 2026Article
- Delayed Minocycline Initiation from Symptom Onset and Severe Outcomes in Japanese Spotted Fever: A Single-Center Retrospective Study in Eastern Hiroshima, Japan.JMA journal · 2026Article
- Rash and Eschar in Japanese Spotted Fever.The American journal of tropical medicine and hygiene · 2026Article
- How rash and eschar came to clinical attention in scrub typhus and Japanese spotted fever.PLoS neglected tropical diseases · 2026Article
- Systemic lupus erythematosus mimicking Japanese spotted fever due to Rickettsia japonica detection in an eschar: a case report.BMC infectious diseases · 2026Article
- Article
- Trends in Japanese Spotted Fever Outbreaks in Fukuyama City of Hiroshima Prefecture in Japan, a High-incidence Area.JMA journal · 2025Article
- Japanese Spotted Fever with Severe Myositis: A Diagnostic Challenge.Internal medicine (Tokyo, Japan) · 2025Article
- Article
- Article
- Deleterious effects of a combination therapy using fluoroquinolones and tetracyclines for the treatment of Japanese spotted fever: a retrospective cohort study based on a Japanese hospital database.The Journal of antimicrobial chemotherapy · 2024Article
- Masqueraders Around Disaster: Clinical Features of Scrub Typhus in Fukushima, Japan.Open forum infectious diseases · 2024Article
- Japanese Spotted Fever with Systemic Leukocytoclastic Vasculitis.Internal medicine (Tokyo, Japan) · 2024Article
- Analysis of Differences in Characteristics of High-Risk Endemic Areas for Contracting Japanese Spotted Fever, Tsutsugamushi Disease, and Severe Fever With Thrombocytopenia Syndrome.Open forum infectious diseases · 2024Article
- Prompt diagnosis and appropriate treatment of Japanese spotted fever: A report of three cases.Heliyon · 2024Article
- Article
- Clinical Characteristics and Diagnostic Prediction of Severe Fever with Thrombocytopenia Syndrome and Rickettsiosis in the Co-Endemic Wakayama Prefecture, Japan.Medicina (Kaunas, Lithuania) · 2023Article
- Nonnegligible Seroprevalence and Predictors of Murine Typhus, Japan.Emerging infectious diseases · 2023Article
- Scrub typhus: the clinical significance of the eschar.BMJ case reports · 2023Article
- Trends in the Incidence of Japanese Spotted Fever in Japan: A Nationwide, Two-Decade Observational Study from 2001-2020.The American journal of tropical medicine and hygiene · 2023Observational
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Japanese spotted fever (JSF) and scrub typhus (ST) are endemic to Japan and share similar clinical features. To document the clinical and epidemiologic characteristics that distinguish these 2 rickettsial diseases, during 2004-2015 we recruited 31 JSF patients, 188 ST patients, and 97 nonrickettsial disease patients from the southern Boso Peninsula of Japan. JSF occurred during April-October and ST during November-December. Patients with JSF and ST were significantly older and more likely to reside in wooded areas than were patients with nonrickettsial diseases. Spatial analyses revealed that JSF and ST clusters rarely overlapped. Clinical findings more frequently observed in JSF than in ST patients were purpura, palmar/plantar rash, hyponatremia, organ damage, and delayed defervescence after treatment. Although their clinical features are similar, JSF and ST differ in seasonality, geographic distribution, physical signs, and severity. Because a considerable percentage of patients did not notice rash and eschar, many rickettsial diseases might be underdiagnosed in Japan.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.