Evidence map›Paper›PMID 30123926›Full record

ReviewCurrent rheumatology reports2018

Role of Infectious Diseases in the Antiphospholipid Syndrome (Including Its Catastrophic Variant).

Claudia Mendoza-Pinto, Mario García-Carrasco, Ricard Cervera

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 96 citations in OpenAlex.

  1. Effect of vitamin DClinics (Sao Paulo, Brazil) · 2024
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  7. Case Report: Neuropsychological Profile of a Patient With Intravascular Large B-Cell Lymphoma Following Infection and Vaccination.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Claudia Mendoza-PintoSystemic Autoimmune Diseases Research Unit, UMAE CMN Manuel Avila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico.
Mario García-CarrascoSystemic Autoimmune Diseases Research Unit, UMAE CMN Manuel Avila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico.
Ricard CerveraDepartment of Autoimmune Diseases, Hospital Clinic, Villarroel, 170, 08036, Barcelona, Catalonia, Spain. rcervera@clinic.cat.
Benemérita Universidad Autónoma de Puebla · MXHospital Clínic de Barcelona · ESMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe antiphospholipid syndrome (APS) is characterized by the development of thrombotic events and pregnancy morbidity in the presence of antiphospholipid antibodies (aPL). An infectious etiology for this syndrome has been postulated. The present review is aimed to summarize recent evidence about the role of infections and vaccines in the pathogenesis of the APS (including its catastrophic variant). RECENT

findingsThere is an increased risk of developing aPL in various infections, particularly in viral infections. The most frequent infection related to aPL has been hepatitis C virus. These antibodies may be associated with thromboembolic events, including catastrophic APS. There is a link between vaccinations, such as the tetanus toxoid and aPL, due to molecular mimicry between the two molecules. Accumulated evidence supports that the presence of aPL is associated with a variety of infections, including viruses, bacteria, fungi, and parasites, and the main mechanism to explain this correlation is molecular mimicry. Moreover, a link between vaccinations, such as the tetanus toxoid, and APS has also been described.

Indexed as

Antiphospholipid SyndromeBacterial InfectionsHepatitis CHumansTetanusVirus DiseasesAntiphospholipid syndromeInfectionsThrombosisVaccines

Identifiers

PMID30123926
OpenAlexW2888169638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.