Evidence map›Paper›PMID 30123922›Full record

ReviewCancer immunology, immunotherapy : CII2019

Monitoring of patients with metastatic melanoma treated with immune checkpoint inhibitors using PET-CT.

Antonia Dimitrakopoulou-Strauss

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Cancer immunology, immunotherapy : CII, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06388252 (Electrochemotherapy Induces Changes in the Tumor Microenvironment of Cutaneous and Subcutaneous Metastases in Patients With Cutaneous Melanoma), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06388252 naenrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Electrochemotherapy Induces Changes in the Tumor Microenvironment of Cutaneous and Subcutaneous Metastases in Patients With Cutaneous Melanoma

TypeinterventionalSponsorInstitute of Oncology LjubljanaRan2023 to 2026Enrolled10ConditionsCutaneous Malignant MelanomaArmsElectrochemotherapy with Intratumoral Cysplatin, Electrochemotherapy with Intravenous Bleomycin
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. The value ofEuropean journal of nuclear medicine and molecular imaging · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. This union must happen: Radiomics and LAFOV PET/CT as the power couple of nuclear medicine.European journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Observational
  8. It Looks Like a Zebra but Is Not: [Diagnostics (Basel, Switzerland) · 2024
    Article
  9. Non-[Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  10. Review on radiomic analysis inCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  11. Can physiologic colonic [European journal of nuclear medicine and molecular imaging · 2023
    Article
  12. Long axial field of view (LAFOV) PET-CT: implementation in static and dynamic oncological studies.European journal of nuclear medicine and molecular imaging · 2023
    Review
  13. Review
  14. Immuno-Imaging (PET/SPECT)-Quo Vadis?Molecules (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. [European journal of nuclear medicine and molecular imaging · 2021
    Article
  20. Imaging in Tumor Immunology.Nuclear medicine and molecular imaging · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Antonia Dimitrakopoulou-StraussClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. a.dimitrakopoulou-strauss@dkfz.de.ORCID http://orcid.org/0000-0003-0338-9472
German Cancer Research Center · DE

Funding

Deutsche Krebshilfe 111241
6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICI) have revolutionized therapy of metastatic melanoma. The first ICI was ipilimumab, a cytotoxic T lymphocyte-associated Ag 4 (CLTA-4) inhibitor with response rates of approximately 11% and disease control of 22%. The programmed cell death 1 (PD-1) inhibitors, such as pembrolizumab and nivolumab, led to longer progression-free survival and overall survival rates with fewer side effects. Molecular imaging techniques, such as positron emission tomography-computed tomography (PET-CT) with 2-deoxy-2-(

Indexed as

Antibodies, Monoclonal, HumanizedHumansImmunotherapyMelanomaMonitoring, PhysiologicNeoplasm MetastasisNivolumabPositron Emission Tomography Computed TomographyProgrammed Cell Death 1 ReceptorResearch DesignAntibodies, Monoclonal, HumanizedNivolumabPDCD1 protein, humanpembrolizumabProgrammed Cell Death 1 ReceptorImmunotherapy monitoringMelanomaPETPIVAC 17

Identifiers

PMID30123922
PMCPMC11028039
OpenAlexW2887435797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.