Evidence map›Paper›PMID 30123780›Full record

ArticleFrontiers in cellular and infection microbiology2018

The Performance of an Oral Microbiome Biomarker Panel in Predicting Oral Cavity and Oropharyngeal Cancers.

Yenkai Lim, Naoki Fukuma, Makrina Totsika, Liz Kenny, Mark Morrison, Chamindie Punyadeera

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Association of Microbiome with Oral Squamous Cell Carcinoma: A Systematic Review of the Metagenomic Studies.International journal of environmental research and public health · 2021
    Pooled it
  2. The Human Microbiome in Relation to Cancer Risk: A Systematic Review of Epidemiologic Studies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Pooled it
  3. Review
  4. Observational
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  7. Article
  8. Review
  9. Review
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  12. HPV Infection and Oral Microbiota: Interactions and Future Implications.International journal of molecular sciences · 2025
    Review
  13. The role of salivary metabolomics in chronic periodontitis: bridging oral and systemic diseases.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  14. Article
  15. Article
  16. Crosstalk Between Oral Microbiome and Cancer: Emerging Trends and Insights.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yenkai LimThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Naoki FukumaThe Department of Life and Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan.
Makrina TotsikaThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Liz KennyThe School of Medicine, University of Queensland, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
Mark MorrisonTranslational Research Institute, University of Queensland Diamantina Institute, University of Queensland, Brisbane, QLD, Australia.
Chamindie PunyadeeraThe School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.
Queensland University of Technology · AUTranslational Research Institute · AUObihiro University of Agriculture and Veterinary Medicine · JPUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral microbiome can play a role in the instigation and progression of oral diseases that can manifest into other systemic conditions. These associations encourage the exploration of oral dysbiosis leading to the pathogenesis of cancers. In this study, oral rinse was used to characterize the oral microbiome fluctuation associated with oral cavity cancer (OCC) and oropharyngeal cancers (OPC). The study cohort consists of normal healthy controls (

Indexed as

MicrobiotaBacteriaBiomarkers, TumorCluster AnalysisDNA, RibosomalDysbiosisHumansMouthMouth NeoplasmsOropharyngeal NeoplasmsPhylogenyRNA, Ribosomal, 16SSensitivity and SpecificitySequence Analysis, DNABiomarkers, TumorDNA, RibosomalRNA, Ribosomal, 16Sbiomarkeroral canceroral microbiomeoral rinsesaliva

Identifiers

PMID30123780
PMCPMC6085444
OpenAlexW2887290460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.