ArticleJournal of International Society of Preventive & Community Dentistry
To Determine the Effect of Chewing Gum Containing Xylitol and Sorbitol on Mutans Streptococci and
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03877705 (Effect of Dissolving Xylitol Chewable Tablets Versus Xylitol Chewing Gum on Salivary pH and Bacterial Count in Geriatric Bedridden Patients), which is not on this map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Dissolving Xylitol Chewable Tablets Versus Xylitol Chewing Gum on Salivary pH and Bacterial Count in Geriatric Bedridden Patients : Randomized Clinical Trial
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Specific effects of xylitol chewing gum on mutans streptococci levels, plaque accumulation and caries occurrence: a systematic review.BMC oral health · 2025Pooled it
- Effects of sugar-free polyol chewing gums on gingival inflammation: a systematic review.Clinical oral investigations · 2022Pooled it
- Antiplaque and antigingivitis efficacy of medicated and non-medicated sugar-free chewing gum as adjuncts to toothbrushing: systematic review and network meta-analysis.Clinical oral investigations · 2022Pooled it
- Effects of xylitol chewing gum and candies on the accumulation of dental plaque: a systematic review.Clinical oral investigations · 2022Pooled it
- Antibacterial Effectiveness and Periodontal Actions of Sugar-Free Chewing Gums Derived From Alcohol or Vegetables in Patients with Fixed Orthodontic Treatment: A Systematic Review.Clinical, cosmetic and investigational dentistry · 2025Review
- Treatment of xerostomia in Sjögren's syndrome - what effect does it have on the oral microbiome?Frontiers in cellular and infection microbiology · 2025Review
- Antibacterial Effect of Miswak herbal toothpaste Compared to Fluoride Toothpaste in High Caries Risk Patients: Randomized Clinical Trial.Journal of clinical and experimental dentistry · 2023Article
- Comparison of Antibacterial Effect of Probiotic Yogurt and Xylitol-Containing Chewing Gum in Geriatric Patients: A Randomized Controlled Clinical Trial.Acta stomatologica Croatica · 2021Article
- Effect of Casein Phosphopeptide Amorphous Calcium Phosphate and Xylitol Chewing Gums, and Probiotic Yogurt on Periodontal Parameters: A Randomized Clinical Trial.Frontiers in dentistry · 2021Article
- Comparative Evaluation of Antibacterial Effect of Propolis and Aloe Vera, Xylitol, and Cpp-Acp Gels onInternational journal of dentistry · 2021Article
- Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils againstPathogens (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIMS AND
objectiveThe aim of the study is to determine the effect of chewing gum containing xylitol and sorbitol on mutans streptococci and MATERIALS AND
methodsThe study was designed as a double-blinded randomized uncontrolled clinical trial with two parallel arms. A total of 80 students consented and completed the study. The test group (X) received corresponding pellets with xylitol and the control group (S) was given pellets containing sorbitol and maltitol three times daily for 30 days. Clinical scoring and saliva samples were collected at three different intervals, at baseline, 15
resultsThere was no statistically significant difference between the mean of mutans streptococci count of test and control group at baseline and 15
conclusionThe results suggest that only xylitol gum may interfere with the mutans streptococci composition and reduce it after continuous use of 30 days effectively as compared to sorbitol gum, but both the gums are equally effective on salivary
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.