ArticleAnnals of thoracic medicine
The pattern of bone involvement, management, and outcomes in patients with nonsmall cell lung cancer: A retrospective study.
Article in Annals of thoracic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis.Cancers · 2023Review
- Impact of Radiotherapy Pattern on the Prognosis of Stage IV Lung Adenocarcinomas Harboring EGFR Mutations.Cancer management and research · 2021Article
- Timing, Sites, and Correlates of Lung Cancer Recurrence.Clinical lung cancer · 2020Article
- Author's Reply.Annals of thoracic medicineArticle
- Pattern of bone metastasis in patients with nonsmall cell lung cancer.Annals of thoracic medicineArticle
- Bone marrow micrometastasis in nonsmall cell lung cancer: A new prognostic marker?Annals of thoracic medicineArticle
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Authors and funding
5 authors.
Funding
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Abstract
CONTEXT AND
aimThe skeleton is a frequent site for metastasis in patients with breast, lung, and prostate cancer. Bone metastasis compromises skeletal integrity leading to skeletal-related events (SREs). This study aims at estimating the prevalence of bone metastasis in lung cancer and describing types of bone involvement, management, outcomes, and overall survival.
methodsWe retrospectively reviewed the charts of 259 patients with nonsmall cell lung cancer who consulted the Department of Medical Oncology at our institution between January 2002 and December 2012. We documented their lung cancer characteristics, presence of skeletal metastases, management types, outcome parameters, and survival status.
resultsA total of 116 patients (58.6%) were diagnosed with bone metastasis. The most common site of metastasis was the spine. The most common SREs were bone pain (44%) and need for radiotherapy (25.9%). Patients with adenocarcinoma (
conclusionMetastatic bone disease is considered a huge burden on patients, clinicians, and the society. The majority of bone metastasis patients will experience SREs. Most SREs predict poor prognosis. Supportive therapy to overcome the reasons for poor prognosis may improve patients' survival and quality of life.
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